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WE INTEND TO INVESTIGATE THE POTENTIAL FOR LIPOSOME ENCAPSULATION OF…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
3105
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
3105
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Therapeutic Delivery Systems
3 Manlon Terrace Buffalo, NY 14225
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: WE INTEND TO INVESTIGATE THE POTENTIAL FOR LIPOSOME ENCAPSULATION OF LYMPHOTOXIN AND ITS DELIVERY TO SPECIFIC LIVER CELLS WHERE LYMPHOTOXIN CAN AUGMENT A NATURAL RESPONSE AGAINST TUMOR.
Agency: HHS
Contract: N/A
Award Amount: $49,645.00
 

Abstract:

WE INTEND TO INVESTIGATE THE POTENTIAL FOR LIPOSOME ENCAPSULATION OF LYMPHOTOXIN AND ITS DELIVERY TO SPECIFIC LIVER CELLS WHERE LYMPHOTOXIN CAN AUGMENT A NATURAL RESPONSE AGAINST TUMOR. UNDERSTANDING HOW THE HOST'S NATURAL DEFENSE SYSTEM CAN BE MODULATED BY CHEMOTHERAPEUTIC DRUGS AND BRMS IN A NUMBER OF PATHOLOGIC STATES IS CRITICAL IN DETERMINING THEIR CLINICAL USEFULNESS. SINCE THE LIVER IS A MAJOR TARGET OF INVASION BY METASTATIC TUMORS, WE HAVE SELECTED IT AS A MODEL ORGAN TO ACCOMPLISH OUR RESEARCH AIMS. WE HAVE DEVELOPED, AND WILL EMPLOY IN THIS PROJECT, TECHNIQUES TO STUDY THE LIVER'S NATURAL ANTITUMOR DEFENSE SYSTEM IN VITRO/EX VITRO AS WELL AS METHODS TO TARGET IMMUNOENHANCING AGENTS TO VARIOUS REGIONS OF THE MURINE LIVER USING LIPOSOMES OF VARIED SIZE AND COMPOSITION.

Principal Investigator:

James r. wilson
PRINCIPAL INVESTIGATOR
7168452025

Business Contact:

Small Business Information at Submission:

Therapeutic Delivery Systems
3 Manlon Terrace Buffalo, NY 14225

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No