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Company Information:

Company Name: THERMOGEN,INC.
City: WOODRIDGE
State: IL
Zip+4: 60517
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (630) 783-4600

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,057,505.00 13
SBIR Phase II $2,993,401.00 5

Award List:

CLONING OF THERMOPHILIC BILIRUBIN OXIDASE GENES

Award Year / Program / Phase: 1989 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $49,675.00

THERMOPHILIC GENE TRANSFER SYSTEM

Award Year / Program / Phase: 1989 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $49,985.00

IN VIVO PROTEIN ENGINEERING SYSTEM

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: David C Demirjian
Award Amount: $49,477.00

THERMOPHILIC GENE TRANSFER SYSTEM

Award Year / Program / Phase: 1991 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $500,000.00
Abstract:
Thermogen, inc., will develop an interspecies genetic transfer system for gram-negative aerobic extreme thermophiles based on plasmids from these organisms. this system will not only function as an important genetic tool for the manipulation of these organisms, but will also allowthe rapid transfer… More

TRANSPOSON BASED TOOLS FOR THERMOPHILIC ORGANISMS

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Demirjian, David C , Principal Investigator
Award Amount: $50,000.00
Abstract:
We will develop mobile genetic elements (transposons) as tools for manipulation of thermophiles, specifically the gram negative thermus sp. these transposons will allow use of sophisticated genetic techniques for the development of durable enzymes for medical and industrial use. the transposons will… More

CLONING OF THERMOPHILIC BILIRUBIN OXIDASE GENES

Award Year / Program / Phase: 1992 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $500,000.00
Abstract:
Thermogen, inc., will develop a therapeutic bioreactor able to inactivate bilirubin. the reactor will be based on a thermostable bilirubin-degrading enzyme produced from a gene cloned from a thermophilic organism. the bioreactor will be able to detoxify bilirubin by extracorporeal or intracorporeal… More

IN VIVO PROTEIN ENGINEERING SYSTEM

Award Year / Program / Phase: 1993 / SBIR / Phase II
Agency: HHS
Principal Investigator: David C Demirjian
Award Amount: $500,000.00
Abstract:
Thermogen, inc., will develop an in vivo protein engineeringsystem allowing rapid, random shuffling of protein domains to produce novel proteins formed by gene fusion. this system will be designed to allow general production of chimeric genes with altered functions, mapping of functionaldomains in a… More

Thermostable Esterases and Lipases

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: HHS
Principal Investigator: Larry Allen
Award Amount: $80,250.00

Thermus Expression System

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Veronika Vonstein
Award Amount: $100,000.00
Abstract:
We will develop a regulated expression system for the extreme thermophile Thermus flavus. This systproduction of commercially important thermostable enzymes. In the Phase I feasibility study we willfrom Thermus, perform minimal structural analyses, and test their regulation using reporter genes… More

Thermostable Esterases and Lipases

Award Year / Program / Phase: 1996 / SBIR / Phase II
Agency: HHS
Principal Investigator: Larry Allen
Award Amount: $743,401.00
Abstract:
We will develop a collection of thermostable esterases and lipases which can be used in chiralsynthesis of new and safer anticancer and antiviral pharmaceuticals. Phase I feasibility will bedemonstrated with discovery of several new enzymes from a variety of extreme- and hyperthermopholicorganisms.… More

SBIR PHASE I: Stable Dehydrogenases: Reagents for Organic Synthesis

Award Year / Program / Phase: 1996 / SBIR / Phase I
Agency: NSF
Principal Investigator: Larry Allen
Award Amount: $75,000.00

NOVEL VIRAL AGENTS FOR CANCER THERAPEUTICS

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Chou, joany
Award Amount: $100,000.00

THERMOSTABLE ENZYMES VIA THERMUS GENOME SEQUENCING

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Vonstein, veronika
Award Amount: $100,000.00

STABLE GLYCOSIDASE LIBRARY FOR THERAPEUTIC SYNTHESIS

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Allen, larry n
Award Amount: $100,000.00

Thermophilic Enzymes Accesed via Thermus

Award Year / Program / Phase: 1998 / SBIR / Phase II
Agency: HHS
Principal Investigator: Vonstein, veronika
Award Amount: $750,000.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Francisco Morisvaras
Award Amount: $113,100.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Francisco Morisvaras
Award Amount: $99,018.00

HIGH THROUGHPUT HYDROLASE SCREENING

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Francisco Morisvaras
Award Amount: $91,000.00
Abstract:
Description: (Applicant's abstract) High throughput screening of biocatalysts is of great relevance for the fields of chemical processing, biotransformation, and drug discovery. Continuous progress in molecular biology, especially DNA cloning and mutagenesis, has facilitated… More