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Company Information:

Name: THIRD WAVE TECHNOLOGIES, INC.
Address: THIRD WAVE TECHNOLOGIES, INC.
506 S ROSA RD
MADISON, WI 53719
Located in HUBZone: No
Woman-Owned: No
Minority-Owned: No
URL: N/A
Phone: (608) 273-8933

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $982,826.00 14
SBIR Phase II $3,626,664.00 6

Award List:

A High Throughput Automated DNA Sequencer

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lance Fors
Award Amount: $49,200.00

Universal System for Directed Nucleic Acid Cleavage

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: HHS
Principal Investigator: Maryann Brow
Award Amount: $75,000.00
Abstract:
We will develop a novel system for directed nucleic acid cleavage. This system is based uponour discovery that the 5' nucleases of several thermostable DNA polymerases can be directed to cleaveas site-specific endonucleases. This system will be thermostable, specific, efficient and… More

SIGNAL AMPLIFICATION FOR SPECIFIC NUCLEIC ACID DETECTION

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: DOE
Principal Investigator: Ms Mary Ann D Brow
Award Amount: $75,000.00

A High Throughput Automated DNA Sequencer

Award Year / Program / Phase: 1995 / SBIR / Phase II
Agency: HHS
Principal Investigator: Lance Fors
Award Amount: $497,240.00
Abstract:
We will commercialize a high-speed instrument for automated DNA sequence analysis. Such an instrument is essential to the success of the Human Genome Initiative; the sequence of the human genome will be determined and used as a powerful tool for biological and medical research. Two key aspects of… More

SIGNAL AMPLIFICATION FOR SPECIFIC NUCLEIC ACID DETECTION

Award Year / Program / Phase: 1995 / SBIR / Phase II
Agency: DOE
Principal Investigator: Ms Mary Ann D Brow
Award Amount: $750,000.00
Abstract:
This project will attempt to commercialize a novel, high-speed, and automatable dna and rna diagnostic technology for the specific detection of nucleic acid sequence changes associated with genetic diseases. this technology is based on the discovery that the 5' nuclease of several thermostable dna… More

QUANTITATIVE THERMOSTABLE EXONUCLEASE DETECTION ASSAY

Award Year / Program / Phase: 1996 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $97,897.00

DETECTION OF RIFAMPIN RESISTANT M TUBERCULOSIS

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Neri, bruce p
Award Amount: $85,308.00

Cflp based determination of hepatitis C virus genotype

Award Year / Program / Phase: 1997 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $600,888.00

NEW METHOD FOR DIRECT AND QUANTITATIVE RNA DETECTION

Award Year / Program / Phase: 1998 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brow, Mary A
Award Amount: $100,000.00

LOW COST HIV DRUG SUSCEPTIBILITY PROFILING

Award Year / Program / Phase: 1998 / SBIR / Phase I
Agency: HHS
Principal Investigator: Kwiatkowski, Robert W
Award Amount: $100,000.00

SPECIFIC AND SENSITIVE MUTATION AND SNP DETECTION

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bruce P. Neri
Award Amount: $100,421.00
Abstract:
Not Available Effective use of large area SIC thyristors has been limited by the decreasing breakdown strength as the size of device increases. The proposed project aims to develop a cost-effective method to greatly improve the breakdown voltage of devices and minimize the dependence of their… More

LOW COST HBV DRUG SUSCEPTIBILITY PROFILING

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Robert W. Kwiatkowski
Award Amount: $100,000.00
Abstract:
Not Available Dynetics, Incorporated proposes to design (Phase I) and develop (Phase I and Phase II) an infrastructure within which the Air Force Research Lab Munitions Directorate can integrate software modules for vulnerability and lethality assessment. The objective of this effort is to address… More

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Hon S. Ip
Award Amount: $0.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase II
Agency: HHS
Principal Investigator: Hon S. Ip
Award Amount: $393,659.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Robert W. Kwiatkowski
Award Amount: $0.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase II
Agency: HHS
Principal Investigator: Robert W. Kwiatkowski
Award Amount: $276,251.00

Genetic Profiles for Perioperative Applications

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Robert W. Kwiatkowski
Award Amount: $100,000.00
Abstract:
The goal of this project over Phase I is to create and test the analytical validity of novel Invader mutation detection assays designed for applications specific to surgery and anesthesia. Invader technology, based on a highly specific enzyme-substrate reaction, enables direct analysis of genomic… More

A HTS GENE EXPRESSION ASSAY FOR SCREENING NUTRACEUTICALS

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Marilyn C. Olson
Award Amount: $100,000.00
Abstract:
The goal of this project is to create a high throughput, sensitive, quantitative and cost-effective platform for measuring gene expression in response to natural compounds derived from foods -nutraceuticals. This technology, the RNA InvaderTM assay, offers highly sensitive detection of mRNA… More

Genetic Profiles for Perioperative Applications

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: HHS
Principal Investigator: Robert W. Kwiatkowski
Award Amount: $0.00
Abstract:
DESCRIPTION (provided by applicant): The objectives of Phase II are to develop, validate, and commercialize a tool for detecting genotypes affecting patient care and safety during the perioperative interval (before, during, and immediately following surgery). Despite publications describing genetic… More

Genetic Profiles for Perioperative Applications

Award Year / Program / Phase: 2003 / SBIR / Phase II
Agency: HHS
Principal Investigator: Robert W. Kwiatkowski
Award Amount: $1,108,626.00
Abstract:
DESCRIPTION (provided by applicant): The objectives of Phase II are to develop, validate, and commercialize a tool for detecting genotypes affecting patient care and safety during the perioperative interval (before, during, and immediately following surgery). Despite publications describing genetic… More