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Compact device for quantitative measurement of in-vivo gas bubble formation

Award Information

Agency:
Department of Defense
Branch:
Navy
Award ID:
83485
Program Year/Program:
2008 / STTR
Agency Tracking Number:
N074-038-0269
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
TIAX LLC
35 Hartwell Avenue Lexington, MA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2008
Title: Compact device for quantitative measurement of in-vivo gas bubble formation
Agency / Branch: DOD / NAVY
Contract: N00014-08-C-0728
Award Amount: $500,125.00
 

Abstract:

We propose to live animal test and continue the refinement of our in-vivo bubble detection system, which quantitatively measures the evolution of gas bubbles in biological tissue and fluid. Our approach utilizes established commercial technology with advanced imaging techniques to permit visualization of microbubble formation without entering the body. The Phase I developed proof-of-concept will be combined with electronic signal processing to quantify the size and density of bubbles as they evolve. We will reduce our laboratory proof-of-concept to a compact prototype that we envision will be used as a tool to help study microbubble formation in an effort to correlate them to the onset of decompression sickness (DCS). The compact prototype will demonstrate the lightweight, low-power, and self-contained nature of the technology. With an eventual DCS correlation, the portability and method of the proposed bubble sensor will ultimately enable personalized dive parameter calculation so divers can operate optimally and safely within their physiological limits.

Principal Investigator:

Vernon E. Shrauger
Associate Principal
6174985172
shrauger.vern@tiaxllc.com

Business Contact:

Renee Wong
Contracting Officer
6174985655
wong.renee@tiaxllc.com
Small Business Information at Submission:

TIAX LLC
15 Acorn Park Cambridge, MA 02140

EIN/Tax ID: 460478749
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
HARVARD UNIV.
Pierce Hall
29 Oxford Street
Cambridge, MA 2138
Contact: David A. Weitz
Contact Phone: (617) 496-2843
RI Type: Nonprofit college or university