USA flag logo/image

An Official Website of the United States Government

Company Information:

Company Name: TRANSDERM, INC.
City: SANTA CRUZ
State: CA
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,028,010.00 4
SBIR Phase II $5,487,953.00 2

Award List:

Pachyonychia congenita clinical trial using therapeutic siRNAs

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $312,655.00
Abstract:
DESCRIPTION (provided by applicant): ABSTRACT RNA interference (RNAi) has the potential to revolutionize treatment of dominant genetic disorders. Small inhibitory RNAs (siRNAs) are highly potent and selective, demonstrating remarkable single-nucleotide spe cificity. Clinical trials using siRNAs are… More

Development of topical rapamycin as a novel treatment for skin disorders

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $226,281.00
Abstract:
DESCRIPTION (provided by applicant): In the decade and a half since the discovery of the underlying mutations in the keratin 5 (K5) and K14 genes in the skin disorder epidermolysis bullosa simplex (EBS), there has been a plethora of additional research ide ntifying the genetic bases of many… More

In vivo imaging models for evaluating siRNA delivery to skin

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $148,215.00
Abstract:
DESCRIPTION (provided by applicant): RNA interference offers the potential of a novel therapeutic approach for treating skin disorders. The technology to design, screen and identify potent, selective, and stable small interfering RNAs (siRNAs) is now rela tively straightforward. The ability to… More

Development of siRNA delivery methodologies using in vivo imaging models

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: HHS
Principal Investigator: Roger L. Kaspar
Award Amount: $1,380,800.00
Abstract:
DESCRIPTION (provided by applicant): RNA interference offers the potential of a novel therapeutic approach for treating skin disorders. The ability to design, screen and identify potent, selective and stable small interfering RNAs (siRNAs) is now relative ly straightforward. Unfortunately,… More

Evaluation of siRNA uptake and functional activity in a human organotypic skin mo

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Roger L. Kaspar
Award Amount: $340,859.00
Abstract:
DESCRIPTION (provided by applicant): Although RNA interference offers high potential as a novel therapeutic approach for treating skin disorders, delivery concerns have hampered their progression to the clinic. The most efficient and effective way to deliv er functionally-active siRNA is through… More

Pachyonychia congenita clinical trial using therapeutic self-delivery siRNAs

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: Roger L. Kaspar – 831-331-3258
Award Amount: $4,107,153.00
Abstract:
DESCRIPTION (provided by applicant): RNA interference (RNAi) has the potential to revolutionize treatment of dominant genetic disorders. Small inhibitory RNAs (siRNAs) are highly potent and selective, demonstrating remarkable single-nucleotide specificity.Clinical trials using siRNAs are currently… More