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Integrated flow cytometer for on-line, real-time unlabeled bio detection in…

Award Information

Agency:
Department of Defense 		Branch:
Army 		Award ID:
74135 		Program Year/Program:
2005 / SBIR
Agency Tracking Number:
A052-243-0720 		Solicitation Year:
N/A 		Solicitation Topic Code:
N/A 		Solicitation Number:
N/A
Small Business Information
Translume
655 Phoenix Drive Ann Arbor, MI -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2005
Title: Integrated flow cytometer for on-line, real-time unlabeled bio detection in potable water
Agency / Branch: DOD / ARMY
Contract: W56HZV-06-C-0091
Award Amount: $69,991.00
 

Abstract:

Quantifying and classifying biological particles (bacteria, viruses, and cells) in drinking water and on beaches is critical to human health and environmental safety. The optimal solution is an on-line, real-time detection system continuously monitoring water without calibration or other attention. This technology has been elusive. Lab-on-a-chip ("LOC") PCR DNA detectors are viable contenders, but are a long way off. Flow cytometry uses optical techniques to detect and classify cells as they flow past in an on-line stream and integrates the cumulative signal to the desired detection level without pre-concentrators (another technology that is some time off). Translume's ability to write optical waveguides and complex microfluidic channels in a glass monolith enables a compact and robust micro flow cytometer (MFC), reducing this complex and delicate instrument into a simple single-piece unit. The MFC will address sample preparation, pre-concentration, and process time, all significant difficulties facing on-line water monitoring systems. Translume proposes to design and prototype an MFC in a single block of glass to determine the viability of this approach to yield a robust and field-deployable device for on-line water monitoring.

Principal Investigator:

Thomas Haddock
VP - Product Development
7345286135
tomhaddock@translume.com

Business Contact:

Eric Jacobson
VP - Finance
7345286371
ericjacobson@translume.com
Small Business Information at Submission:

TRANSLUME
655 Phoenix Drive Ann Arbor, MI 48108

EIN/Tax ID: 383586672
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No