USA flag logo/image

An Official Website of the United States Government

Picogram Non-Specific DNA Detection System

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
25111
Program Year/Program:
1994 / SBIR
Agency Tracking Number:
25111
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
TREVIGEN, INC.
8405 HELGERMAN COURT GAITHERSBURG, MD 20877-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1994
Title: Picogram Non-Specific DNA Detection System
Agency: HHS
Contract: 1 R43 GM51153-1,
Award Amount: $79,125.00
 

Abstract:

Based on preliminary results, construction of a general system for detection of DNA at thepicogram (1 x 10(-12)) level may be possible. The system would work in most aqueous solutionswithout regard to the sequence of the DNA. As proposed, it does not require sophisticatedinstrumentation and should be able to detect DNA in samples for a reagent cost of about 50 cents perassay.In particular, the system will be able to detect DNA in the presence of large amounts of proteins,carbohydrates, and small molecules. Components of the system are commercially available. The keyto making a commercially viable system is validation of the assay technique under conditions likely tobe of interest and benefit to potential customers, people doing laboratory research and pharmaceuticalproduction. A simple and reliable method of quantitating DNA concentration in complex mixtures isneeded. Without purifying DNA, no sequence independent method is available.

Principal Investigator:

Gordon Collier
3012162800

Business Contact:

Small Business Information at Submission:

Trevigen, Inc.
8405 Helgerman Court Gaithersburg, MD 20877

EIN/Tax ID: 521797207
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No