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Alkenylguanine Analogs--A New Class of Antiviral Agent

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29094
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29094
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Triplex Pharmaceutical
9391 Grogans Mill Road The Woodlands, TX 77380
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Woman-Owned: No
Minority-Owned: Yes
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Alkenylguanine Analogs--A New Class of Antiviral Agent
Agency: HHS
Contract: 1 R43 AI36788-01A1,
Award Amount: $100,000.00
 

Abstract:

We will develop certain structure activity relationships with respect to a novel class of antiviralconduct preliminary experiments designed to define the mechanism of action for these drugs. Preliminestablished that certain alkenes, when attached to a guanine congener, provide potential antiviral atherapeutic indices against debilitating, human, DNA viral infections . We will synthesize additionaactive compounds wherein certain structural variations will be made in the unsaturated hydrocarbon mcomparison of the antiviral activity of these additional derivatives will be used to construct a hypstructural features suggesting the most promising drug candidate. Information from simultaneous studof antiviral action of these drugs will be incorporated into the development of the model.

Principal Investigator:

Arthur Lewis
71363

Business Contact:

Small Business Information at Submission:

Triplex Pharmaceutical
9391 Grogans Mill Road The Woodlands, TX 77380

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No