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CLASSIFICATION OF MAMMOGRAPHIC MICROCALCIFICATION

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
19123
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
19123
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
UES, Inc.
4401 Dayton-Xenia Road Dayton, OH 45432-
View profile »
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1992
Title: CLASSIFICATION OF MAMMOGRAPHIC MICROCALCIFICATION
Agency: HHS
Contract: N/A
Award Amount: $49,984.00
 

Abstract:

MASS SCREENING USING MAMMOGRAPHY IS, AT PRESENT, THE ONLY VIABLE AND EFFECTIVE METHOD TO DETECT BREAST CANCER. IT IS DIFFICULT, HOWEVER, TO DISTINGUISH BETWEEN BENIGN AND MALIGNANT MICROCALCIFICAITONS ASSOCIATED WITH BREAST CANCER. THIS DIFFICULTY RESULTS IN A SIGNIFICANT INCREASE IN THE NUMBER OF BIOPSY EXAMINATIONS. MOST OF THE MINIMAL BREAST CANCERS ARE CURRENTLY DETECTED BY THE PRESENCE OF MICRO-CALCIFICATIONS. THE MAJOR PROBLEMS ARE THE RELATIVELY LOW-POSITIVE PREDICTIVE VALUE AND THE HIGH FALSE-POSITIVE RATE NECESARY TO MAXIMIZE SENSITIVITY FOR MINIMAL BREAST CANCER DETECTION. IT IS THE LONG-TERM (PHASE I AND PHSE II) OBJECTIVE OF THIS PROJECT TO BE ABLE TO REDUCE THE FALSE-POSITIVE RATE OF BREAST CANCER DETECTION, WHILE MAINTAINING HIGH SPECIFICITY. THE OBJECTIVE OF PHASE I IS TO DEVELOP A COMPUTERIZED ARTIFICAL NEURAL NETWORK-BASED MAMMOGRAM ANALYSIS SYSTEM. BASIC STEPS INCLUDE FEATURE SELECTION FOR THE MICROCALCIFICATION REGIONS IN THE MAMMOGRAMS, DESIGNING AND TRAINING THE NEURAL NETWORK, AND TESTING AND VERIFICATION OF CLASSIFICATION ACCURACY OF NEURAL NETWORK ALGORITHMS. IMAGE STRUCTURE FEATURES WILL BE SELECTED FROM A SET OF MAMMOGRAMS WITH BENIGN AND MALIGNANT MICROCALCIFICATIONS TO PROVIDE GOOD DISCRIMINATION BETWEEN THEM. THE SYSTEM WILL POSSESS THE ABILITY TO ACCURATELY SEGMENT SUCH REGIONS. THIS SYSTEM CAN BE SUBSEQUENTLY REFINED TO PROVIDE HIGH SPECIFICITY.

Principal Investigator:

Alok Sarwal
5134266900

Business Contact:

Small Business Information at Submission:

Ues Inc
5162 Blazer Pkwy Dublin, OH 43017

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No