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TANTALUM FOAMS FOR CANCELLOUS BONE IMPLANTS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
19188
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
19188
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Ultramet
12173 Montague Street Pacoima, CA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1995
Title: TANTALUM FOAMS FOR CANCELLOUS BONE IMPLANTS
Agency: HHS
Contract: N/A
Award Amount: $493,388.00
 

Abstract:

THE NEED FOR A CANCELLOUS BONE SUBSTITUTE, IN THE FORM OF AN ARTIFICIAL BIOCOMPATIBLE IMPLANT, IS SIGNIFICANT. RESEARCH HAS DEMONSTRATED THAT AN IMPLANT IDEALLY SHOULD SERVE AS A POROUS FRAMEWORK FOR BONE REGENERATION. IN THIS PROGRAM, WE WILL USE A NOVEL BIOMEDICAL APPLICATION OF A MATERIAL ORIGINALLY DEVELOPED FOR NONMEDICAL PURPOSES. RETICULATED CARBON FOAM WILL BE INFILTRATED WITH TANTALUM BY CHEMICAL VAPOR INFILTRATION (CVI), A VARIATION OF THE CHEMICAL VAPOR DESPOSITION (CVD)PROCESS. TANTALUM HAS A LONG HISTORY OF USE AS AN IMPLANT MATERIAL, IN BOTH BONE AND SOFT TISSUE. IN PHASE I, ULTRAMET WILL DEMONSTRATE THE FEASIBILITY OF PRODUCING TANTALUM UM FOAMS IN SEVERAL POROSITIES AND CONFIGURATIONS, AND THE CVI PROCESS FOR TANTALUM WILL BE REFINED AND INITALLY OPTIMIZED. THE MATERIALS FABRICATED BY ULTRAMET WILL THEN BE EVALUATED BY THE DEPARTMENT OF BIOENGINEERING. CLEMSON UNIVERSITY, WHICH WILL CONDUCT EXTENSIVE MECHANICAL TESTING AND CORROSION STUDIES. THE RESULTS OF THE MECHANICAL TESTS PERFORMED ON RETICULAR TANTALUM WILL BE COMPARED TO ACCEPTED VALUES FOR CANCELLOUS BONE. THIS LIGHTWEIGHT, STRONG, POROUS STRUCTURE, MIMICKING THE MICROSTRUCTURE OF NATURAL CANCELLOUS BONE, WILL ACT AS MATRIX FOR THE INCORPORATION OF BONE, PROVIDING OPTIMAL PERMEABILITY AND A HIGH SURFACE AREA TO ENCOURAGE NEW BONE INGROWTH.

Principal Investigator:

Richard B Kaplan
8188990236

Business Contact:

Small Business Information at Submission:

Ultramet
12173 Montague Street Pacoima, CA 91331

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No