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BIOSENSORS FOR RAPID DETECTION OF SEAFOOD TOXINS

Award Information

Agency:
Department of Commerce
Branch:
N/A
Award ID:
14674
Program Year/Program:
1991 / SBIR
Agency Tracking Number:
14674
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Universal Sensors, Inc.
5258 Veterans Blvd., Suite D Metairie, LA 70006
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1991
Title: BIOSENSORS FOR RAPID DETECTION OF SEAFOOD TOXINS
Agency: DOC
Contract: N/A
Award Amount: $35,000.00
 

Abstract:

IN PHASE 1 AN ELECTROCHEMICAL IMMUNOBIOSENSOR WILL BE DEVELOPED FOR INEXPENSIVE, RAPID, IN-FIELD DETECTION OF BREVETOXINS IN FISH TISSUE AND MARINE SAMPLES. THE BIOSENSOR WILL BE COMPRISED OF A WORKING ELECTRODE COVERED WITH IMMOBILIZED ANTIGEN AND A REFERENCE ELECTRODE, BOTH MOUNTED IN A SYRINGE NEEDLE. TOXIN CONCENTRATION WILL BE DETERMINED BY COMPETITIVE, HETEROGENEOUS, IMMUNOASSAY; SAMPLE BREVETOXIN WILL COMPETE WITH IMMOBILIZED TOXIN FOR GLUCOSE OXIDASE-LABELED ANTIBODY. AFTER REMOVAL OF EXCESS SAMPLE, THE ENZYME LABEL WILL BE DEVELOPED TO PRODUCE A CURRENT INVERSELY PROPORTIONAL TO TOXIN CONCENTRATION. CHAOTROPES, SUCH AS 10 MM HC1, WILL BE USED TO REGENERATE THE IMMUNOSENSOR FOR REUSE. THE BIOSENSOR WILL BE EASY TO OPERATE, PORTABLE, SELECTIVE, AND SENSITIVE (PPT). IN PHASE2, A RANGE OF IMMUNOBIOSENSORS FOR OTHER MARINE BIOTOXINS SUCH AS, SAXITOXIN, TETRODOTOXIN, AND PALYTOXIN WILL BE DEVELOPED. THESE SENSORS WILL BE INCORPORATED INTO A MINIATURIZED FLOW INJECTION ANALYSIS INSTRUMENT FOR RAPID, AUTOMATED, AND INEXPENSIVE, IN-FIELD, MULTITOXIN ANALYSIS OFFISH TISSUE AND MARINE SAMPLES.

Principal Investigator:

Dr Graham Ramsay
5048858443

Business Contact:

Small Business Information at Submission:

Universal Sensors Inc
5258 Veterans Blvd Suite D Metairie, LA 70006

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No