Fiscal Year:
2007
Title:
STTR Phase I: Monolithic Multiwavelength Blue-to-IR LED for Biomedical Diagnostics
Agency:
NSF
Contract:
0712295
Award Amount:
$149,761.00
Abstract:
This Small Business Technology Transfer (STTR) Phase I project will demonstrate the feasibility of a novel multi-wavelength light-emitting diode (LED) for transdermal health monitoring of various blood metabolites simultaneously in real time. With independent control of up to 12 spectrally narrow wavelengths, ranging from deep-UV to mid-IR, from a single 1 mm2 LED die, the company's compact multi-wavelength LED will revolutionize traditional pulse oximetry with unprecedented functionality at a significantly lower cost. In contrast with traditional dual-wavelength pulse oximetry, which primarily measures the ratio of oxygenated to deoxygenated blood, the proposed multi-wavelength LED will enable the real-time analysis several additional metabolites critical to health monitoring via the same noninvasive paradigm. Furthermore, combining 12 LEDs into one self-aligned device precludes the need for expensive packaging and complex optical alignment.The medical impact of dual-wavelength pulse oximetry, in both saving lives and reducing healthcare costs, has encouraged the development of broader platforms using additional optical wavelengths. Incorporating 3 or more independently controlled wavelengths has been shown to enable the real-time monitoring of multiple health factors while further reducing readout errors - thus saving more lives. Beyond blood oxygen monitoring, a real-time noninvasive assessment of renal and hepatic health can be realized by integrating several wavelengths in the same clinically accepted pulse oximetry paradigm. The proposed multi-wavelength single-die approach surmounts these limitations by providing independent control of several wavelengths from a single, self-aligned, compact LED. Integrating these advanced, cost-effective optical sources into traditional pulse oximetry opens up new markets in noninvasive metabolic monitoring for paramedics, physical therapists, drug discovery, and home healthcare. As a spectroscopic source, other applications include air-quality/pollution monitoring and agricultural/industrial controls.
Small Business Information at Submission:
Valencell
920 Main Campus Drive 6745 HOLLISTER AVENUE Raleigh, NC 27606
EIN/Tax ID:
205493056
DUNS:
N/A
Number of Employees:
Woman-Owned:
No
Minority-Owned:
No
HUBZone-Owned:
No
Research Institution Information:
North Carolina State Univ
Compus Box 7514
Raleigh, NC 27695-2470
Contact:
John F. Muth
Contact Phone:
(919) 513-2982
RI Type:
Nonprofit college or university