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STTR Phase I: Monolithic Multiwavelength Blue-to-IR LED for Biomedical…

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
84933
Program Year/Program:
2007 / STTR
Agency Tracking Number:
0712295
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Valencell Inc.
2800-154 sumner blvd RALEIGH, NC 27616-2970
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2007
Title: STTR Phase I: Monolithic Multiwavelength Blue-to-IR LED for Biomedical Diagnostics
Agency: NSF
Contract: 0712295
Award Amount: $149,761.00
 

Abstract:

This Small Business Technology Transfer (STTR) Phase I project will demonstrate the feasibility of a novel multi-wavelength light-emitting diode (LED) for transdermal health monitoring of various blood metabolites simultaneously in real time. With independent control of up to 12 spectrally narrow wavelengths, ranging from deep-UV to mid-IR, from a single 1 mm2 LED die, the company's compact multi-wavelength LED will revolutionize traditional pulse oximetry with unprecedented functionality at a significantly lower cost. In contrast with traditional dual-wavelength pulse oximetry, which primarily measures the ratio of oxygenated to deoxygenated blood, the proposed multi-wavelength LED will enable the real-time analysis several additional metabolites critical to health monitoring via the same noninvasive paradigm. Furthermore, combining 12 LEDs into one self-aligned device precludes the need for expensive packaging and complex optical alignment.The medical impact of dual-wavelength pulse oximetry, in both saving lives and reducing healthcare costs, has encouraged the development of broader platforms using additional optical wavelengths. Incorporating 3 or more independently controlled wavelengths has been shown to enable the real-time monitoring of multiple health factors while further reducing readout errors - thus saving more lives. Beyond blood oxygen monitoring, a real-time noninvasive assessment of renal and hepatic health can be realized by integrating several wavelengths in the same clinically accepted pulse oximetry paradigm. The proposed multi-wavelength single-die approach surmounts these limitations by providing independent control of several wavelengths from a single, self-aligned, compact LED. Integrating these advanced, cost-effective optical sources into traditional pulse oximetry opens up new markets in noninvasive metabolic monitoring for paramedics, physical therapists, drug discovery, and home healthcare. As a spectroscopic source, other applications include air-quality/pollution monitoring and agricultural/industrial controls.

Principal Investigator:

Steven F. LeBoeuf
Dr
9197936977
leboeuf@valencell.com

Business Contact:

Steven F. LeBoeuf
PhD
9197936977
leboeuf@valencell.com
Small Business Information at Submission:

Valencell
920 Main Campus Drive 6745 HOLLISTER AVENUE Raleigh, NC 27606

EIN/Tax ID: 205493056
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
North Carolina State Univ
Compus Box 7514
Raleigh, NC 27695-2470
Contact: John F. Muth
Contact Phone: (919) 513-2982
RI Type: Nonprofit college or university