Award Year / Program / Phase:2009 / STTR / Phase II
Agency:HHS
Research Institution:UNIVERSITY OF NORTH CAROLINA CHAPEL HILL
Principal Investigator:David R. Clemmons
Award Amount:$1,218,285.00
RI Contact:N/A
Abstract:
DESCRIPTION (provided by applicant): The long term objective of the proposed studies is to develop a monoclonal antibody that can be administered safely to patients with diabetes that will inhibit atherosclerosis. Insulin-like growth factor-I has been impl
icated in the initiation of the… More
DESCRIPTION (provided by applicant): The long-term objective of the proposed study is to develop a monoclonal antibody that inhibits the progression of diabetic retinopathy. Insulin-like growth factor-I (IGF-I) has been implicated in both endothelial dysfunction as well as the proliferative phase of… More