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VIRTUAL PINHOLE CONFOCAL MICROSCOPE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
60157
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
RR014117
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
VAYTEK, INC.
VAYTEK, INC. 305 W LOWE, STE 109 FAIRFIELD, IA 52556
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2002
Title: VIRTUAL PINHOLE CONFOCAL MICROSCOPE
Agency: HHS
Contract: 2R44RR014117-02A2
Award Amount: $780,000.00
 

Abstract:

DESCRIPTION (provided by applicant)We have developed a novel system for confocal microscopy-the Virtual Pinhole Microscope-that promises a number of advantages over conventional confocal instruments: reduced cost, faster imaging, improved efficiency and sensitivity, improved reliability and much greater flexibility. Phase I work established the feasibility of all component systems, and the functionality of the integrated system. Proposed Phase II work will complete the technical development cycle and result in a powerful and low-priced product. We will continue to develop a novel system for high performance illumination, patterned in time and space. We will refine and fabricate a system for high performance data acquisition and processing, designed to support real-time confocal imaging. We will extend, further develop, evaluate and validate both static and adaptive algorithms used to reconstruct confocal images from a time series of spatially sub-sampled images. We will integrate component systems, to produce two configurations of the instrument. Phase III work will include development of documentation and a beta test program. The confocal systems developed with SBIR support will allow the collection of high quality confocal images in fluorescence, reflectance and transmission modes with equipment that can be inexpensively retrofit to existing microscopes, and will enable important new application.

Principal Investigator:

John B. Kesterson
6414722227
JKESTERSON@LISCO.COM

Business Contact:

John Kesterson
5154722227
JKESTERSON@LISCO.COM
Small Business Information at Submission:

VAYTEK, INC.
VAYTEK, INC. 305 W LOWE, STE 109 FAIRFIELD, IA 52556

EIN/Tax ID: 421350463
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No