The QuantiFERON-TB Gold In-Tube (QFT-GIT), developed by Cellestis Ltd., is an in-vitro diagnostic test using a peptide cocktail simulating ESAT-6, CFP-10 and TB7.7(p4) proteins to stimulate cells in heparinized whole blood. Detection of interferon-gamma (IFN-g) by Enzyme-Linked Immunosorbent Assay… More

The FHIE/BHIE initiative links DoD AHLTA with VHA Vista. The existing architecture is based on HL7 V2.x. We propose a method for migrating this architecture to the HL7 V3 RIM and the HL7 V3 CDA (rel 2). The proposed approach retains the core components of the FHIE architecture while replacing only… More

We propose an approach to fuse open-source, intelligence and medical surveillance data into an integrated information technology system capable of providing the commander with early indications and warnings of a possible bioevent. The software tool will make positive identifications of bioevent… More

Distributed logistics problems cannot be solved using traditional centralized optimization techniques because of the autonomous nature of the entities involved. We propose to design and demonstrate a decentralized automated negotiation based approach. This game theoretic approach is implemented as a… More

Search, analysis and display of NASA science data by non-GIS experts can be facilitated using so-called "Web 2.0" technologies. Google Maps is a popular geospatial service which exemplifies the use of such technologies. Browser-based client-side mashups and overlays of various kinds of data sources… More

Existing adversary models do not adequately capture the asymmetric behavior of the new threats faced by the US military. For example, asymmetric adversary models need to reflect the loosely-knit organizational structure of terrorist groups. These new models should learn to adapt to the trainee's… More

The FHIE/BHIE initiative links DoD AHLTA with VHA Vista. The existing architecture is based on HL7 V2.x. We propose a method for migrating this architecture to the HL7 V3 RIM and the HL7 V3 CDA (rel 2). The proposed approach retains the core components of the FHIE architecture while replacing only… More

In any large-scale training exercise, it is difficult to provide all trainees with training objectives commensurate with their skills levels, experience or expertise. There are three main components needed for the solicited toolkit. The toolkit must provide suitable algorithms for assessment and… More

Mission assured networking (MAN) is a capability for mapping mission tasks to information technology (IT) resources in a highly dynamic environment where both tasks and resources change rapidly. Autonomic MAN would permit such task-resource allocations to be performed in a bottom-up decentralized… More

A computational analysis management system (CAMS) is different from typical content management systems (CMS)in that a CAMS provides much more in-depth meta-data relating numbers-based documents with each other. Such meta-data should address questions such as who created this document and why; how is… More

We propose agent-based game-theoretic approaches for simulation of strategies involved in multi-objective collaborative traffic flow management (CTFM). Intelligent agents represent two types of entities / players: FAA Traffic Management Unit (TMU) representatives, and Airline Operations Center (AOC)… More

In any large-scale training exercise, it is difficult to provide all trainees with training objectives commensurate with their skills levels, experience or expertise. The TARGETS and EBAT training and performance measurement methodologies were developed by Dr. Eduardo Salas at UCF. In this project,… More

Sensor Web Enablement (SWE) is an Open Geospatial Consortium (OGC) standard Service Oriented Architecture (SOA) that facilitates discovery and integration of web-enabled sensor data. We propose two enhancements to SWE. One is the creation of Semantic Sensor Web Enablement (SSWE) through the… More

Next-gen AFSCN scheduling software will need to incorporate two aspects that are missing from existing solutions. One is the need to incorporate fuzzy time constraints and dynamic priorities. The other aspect is the need to provide support to the manual negotiations that currently take place between… More

We propose a systems engineering based approach for battle management that utilizes a game theoretic resource optimization method. We explicitly consider adversary tactics in the two-sided optimization formulation. We propose an efficient parallel computing oriented optimization solution for the… More

DOE's Systems Biology Knowledgebase (SBK) needs semantic web tools, in particular, a semantic search engine, for integrating existing and emerging databases like MetaCyc and PubMed. We propose to leverage existing ontologies such as GO and UMLS to create a global ontology that automatically merges… More

The resource allocation problem and the associated resource management solution is composed of three levels. At the highest level is the game theoretic mapping of alternative offense and defense actions, much like a chess game. At the next level is the large-scale efficient mathematical optimization… More

For effective disaster response, software technology needs to provide several key features: enable real-time reporting of events, aggregate and analyze event reports in real-time, display event reports on maps (2D) and geobrowsers (3D). We propose to leverage several leading-edge software… More