This Small Business Innovation Research (SBIR) Phase II project aims to develop an automated instrument for rapid and specific detection of waterborne pathogens in municipal water supplies using methods combining immunoassay with electrochemistry. Although the disposable cartridges for this… More

Cryptosporidium parvum, a waterborne pathogen, is a serious threat to the Nation¿s water supply. It does not respond to common antibiotics and resists water purification treatments. It is of interest to not only monitor C. parvum oocysts in drinking water, but also to study their fate in the… More

This Small Business Innovation Research (SBIR) Phase I research project is to develop an electrochemical detection method for analysis of liver stage plasmodium falciparum malaria parasites, with the intent of eliminating interferences, while achieving speed and sensitivity. The commercial… More

This Small Business Innovation Research (SBIR) Phase II project aims to develop an automated instrument for rapid and specific detection of waterborne pathogens in municipal water supplies using methods combining immunoassay with electrochemistry. Although the disposable cartridges for this… More

Cryptosporidium parvum, a protozoan parasite that invades the gastrointestial system, is a serious threat to the nation's water supply. Assays for pathogen using self-contained microelectrochemical detection are desirable because precise detection can be performed with simple instrumentation on… More

This Small Business Innovation Research (SBIR) Phase I project will use a novel self-contained micro-electrochemical detection technology to measure the human protein response to specific biological agents. The end result will be an embedded computer controlled, automated, hand held device that… More

This Small Business Innovation Research (SBIR) Phase II project focuses on the development of an automated, high-throughput, sensitive and specific assay for the micorelectrochemical detection of malaria parasites. The use of microelectrochemical assay will allow for the detection of malarial… More

Cryptosoridium is a resilient waterborne protozoan pathogen that caused gastrointestinal disease and is one of five major causes for 5 million deaths each year worldwide. Recently, a Cryptosoridium outbreak has sickened more than 1,700 people, mostly children and teenagers in New York. … More

This Small Business Technology Transfer (STTR) Phase I project will develop a self-contained microelectrochemical assay array for simultaneous and quantitative detection of allergens in dust such as dust mites, cat dander, and cockroach allergens. Allergies cause illness and disabilities that affect… More

This Small Business Technology Transfer (STTR) Phase I project is to develop a novel and commercially scalable method for fabricating integrated carbon nanopipes (nanopipettes). The carbon nanopipettes (CNP) have a wide variety of potential applications both for liquid delivery and as nanoelectrodes… More

DESCRIPTION (provided by applicant): The main goal of this Phase I SBIR project is to optimize the fabrication process and demonstrate the feasibility of using a novel carbon-based nanopipette (CNP electroprobe) for penetration of cell membrane in single c ells with minimal cell intrusion and allow… More

DESCRIPTION (provided by applicant): Vegrandis proposes to develop a rapid, sensitive, high throughput, inexpensive, and easy to use system for the ante-mortem diagnosis of prion infection. The proposed system offers a fully automated equipment with a disp osable microelectrochemical cartridge for… More

DESCRIPTION (provided by applicant): The main goal of this Phase I SBIR project is to demonstrate the feasibility of using a novel carbon-based nanopipette (CNP) for precise and controlled microinjection of macromolecules into single cells and allow electr ical measurement of variations in membrane… More