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Recombinant human serum albumin for therapeutic use

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
79783
Program Year/Program:
2006 / SBIR
Agency Tracking Number:
HL083551
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
VENTRIA BIOSCIENCE
320 East Vine Drive FORT COLLINS, CO -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2006
Title: Recombinant human serum albumin for therapeutic use
Agency: HHS
Contract: 1R43HL083551-01
Award Amount: $99,500.00
 

Abstract:

DESCRIPTION (provided by applicant): Due to the potential risk of disease contamination of human serum albumin (HSA) derived from fractionation of pooled donor blood and the increasing demand of HSA in therapeutic applications, production of recombinant human serum albumin (rHSA) has become attractive as an alternative to blood-derived HSA. While significant progress has been made in various protein expression systems, particularly in yeast, the cost of rHSA production is very high. Due to a large capital requirement, the scale of rHSA production is limited and will not be able to meet the market demand. Ventria Bioscience has developed a proprietary protein expression system, ExpressTec, and has recently used it to express rHSA in rice grain with an expression level of 8 gram/kg flour weight (40% total soluble protein) which is 4 to 100 folds higher than other expression systems. Rice grain can be produced at cost of less than <0.22 /kg thus rHSA derived from rice can be produced at

Principal Investigator:

Ning Huang
9169216148
NHUANG@VENTRIA.COM

Business Contact:

Ning Huang
9169216148
NHUANG@VENTRIA.COM
Small Business Information at Submission:

VENTRIA BIOSCIENCE
VENTRIA BIOSCIENCE 4110 N FREEWAY BLVD SACRAMENTO, CA 95834

EIN/Tax ID: 680310843
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No