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THE OBJECTIVE OF THIS PROJECT IS TO DEMONSTRATE THE FEASIBILITY OF EFFICIENTLY…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
2902
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
2902
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Verax Corp
Etna Rd Hc 61 Box 6 Lebanon, NH 03766
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: THE OBJECTIVE OF THIS PROJECT IS TO DEMONSTRATE THE FEASIBILITY OF EFFICIENTLY PRODUCING BIOCHEMICALS FROM MAMMALIAN FIBROBLASTS BY A NOVEL METHOD OF CONTINUOUS CULTURE WITH IMMOBILIZED CELLS.
Agency: HHS
Contract: N/A
Award Amount: $38,378.00
 

Abstract:

THE OBJECTIVE OF THIS PROJECT IS TO DEMONSTRATE THE FEASIBILITY OF EFFICIENTLY PRODUCING BIOCHEMICALS FROM MAMMALIAN FIBROBLASTS BY A NOVEL METHOD OF CONTINUOUS CULTURE WITH IMMOBILIZED CELLS. THE NOVELTY OF THIS METHOD CENTERS ON A UNIQUE CELL CARRIER, WHICH ALLOWS FOR A HIGH DENSITY OF CELL PACKING AND FOR MONTHS OF CONTINUOUS CELL GROWTH AND BIOCHEMICAL PRODUCTION. SUPPORTING THE UNIQUE MATRIX ARE A PROPRIETARY BIOREACTOR DESIGN AND SPECIAL MEDIUM FORMULATIONS. THE LOWER COST OF PRODUCING BIOCHEMICALS, WHICH RESULTS FROM THIS METHODOLOGY, WILL ENCOURAGE THEIR MEDICAL AND VETERINARY USE. THE WORK PLAN IS DESIGNED TO ADAPT A VERAX PROPRIETARY CELL-IMMOBILIZING MATRIX FOR THE GROWTH OF MOUSE FIBROBLASTS. THIS WILL BE DONE BY MAKING PHYSICAL AND CHEMICAL CHANGES, DURING THE MANUFACTURE OF THE MATRIX, AND TESTING FOR THE LONG-TERM PERFORMANCE OF CELLS WITHIN THESE MODIFIED MATRICES. ALONG WITH MATRIX DEVELOPMENT, VARIOUS MEDIUM FORMULATIONS WILL BE TESTED FOR THEIR ABILITY TO ENHANCE PRODUCTION OF BIOCHEMICALS BY IMMOBILIZED CELLS. WE EXPECT TO DEMONSTRATE THE VALUE OF EXTENDING THIS FEASIBILITY STUDY, THROUGH A PHASE II SBIR GRANT, TO AN IN-DEPTH ADAPTATION OF VERAX'S TECHNOLOGY FOR MASS PRODUCTION OF ANY FIBROBLAST-DERIVED PRODUCT.

Principal Investigator:

Philip g. phillips
PRINCIPAL INVESTIGATOR
6034484445

Business Contact:

Small Business Information at Submission:

Verax Corpon
P.o. Box B1170 Hanover, NH 03755

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No