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METAL ISOTOPE RATIOS BY LD/TOF MASS SPECTROMETRY

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
19169
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
19169
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Vestec Corpon
9299 Kirby Dr Houston, TX 77054
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1992
Title: METAL ISOTOPE RATIOS BY LD/TOF MASS SPECTROMETRY
Agency: HHS
Contract: N/A
Award Amount: $49,990.00
 

Abstract:

THE OVERALL GOAL OF THIS PROJECT IS TO DEVELOP A NEW LASER DESORPTION TIME-OF-FLIGHT (LD/TOF) MASS SPECTROMETRIC TECHNIQUE FOR THE DETERMINATION OF METAL ISOTOPE RATIOS THAT CAN BE READILY APPLIED TO STUDIES OF THE METABOLISM OF BIOLOGICALLY SIGNIFICANT BULK AND TRACE ELEMENTS. THE PHASE I GOALS OF THIS PROJECT ARE TO DEMONSTRATE THE FEASIBILITY OF AN INSTRUMENT THAT COMBINES THE FEATURES OF THE HIGH ACCURACY AND PRESCISION OF THERMAL IONIZATION WITH THE SENSITIVITY, SPEED, AND FREEDOM FROM MEMORY EFFECTS OF THE LD/TOF INSTRUMENT. THIS NEW INSTRUMENT SHOULD PROVIDE BROAD APPLICABILITY TO METALS SIMILAR TO INDUCTIVELY COUPLED PLASMA (ICP) IONIZATION OR FAB/SIMS MASS SPECTROMETRY WITHOUT THE INTERFERING MATRIX EFFECTS. SUCCESSFUL COMPLETION OF THE RESEARCH WILL PROVIDE A GENERALLY APPLICABLE MASS SPECTROMETRIC TECHNIQUE FOR METAL TRACER STUDIES WITH BETTER PERFORMANCE THAN THAT OBTAINED BY THERMAL IONIZATION, AND WHICH IS FASTER AND EASIER TO USE AND REQUIRES SMALLER ABSOLUTE SAMPLE AMOUNTS.

Principal Investigator:

Marvin L Vestal
7137969677

Business Contact:

Small Business Information at Submission:

Vestec Corpon
9299 Kirby Dr Houston, TX 77054

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No