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Computerized Addiction Prevention for Opioid Prescribing

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
71459
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
DA018527
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
WATERFORD LIFE SCIENCES
1666 CONNECTICUT AVE, NW, SUITE 500 WASHINGTON, DC 20009
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2004
Title: Computerized Addiction Prevention for Opioid Prescribing
Agency: HHS
Contract: 1R43DA018527-01
Award Amount: $98,438.00
 

Abstract:

DESCRIPTION (provided by applicant): This Phase I application proposes to test the feasibility of AESOP (Assessment and Evaluation for Safe Opioid Prescribing), an integrated suite of software tools that will enable primary care physicians to prevent prescription drug abuse and addiction during long-term opioid therapy. Currently there is no interactive software incorporating validated assessment and treatment protocols for pain management with opioids. AESOP will serve this growing and umet need by offering primary care physicians a computer-assisted algorithm to: (1) assess patients for opioid therapy based on a detailed personal, medical and pain management history (2) identify patients at high risk for addiction or abuse (3) educate patients about risks and benefits of long-term opioid therapy (4) institute waiting periods to discourage "doctor-shopping" and illicit drug-seeking, (5) implement customized doctor-patient agreements to increase adherence and minimize abuse and diversion, (6) monitor patients at subsequent prescribing visits via in-depth assessment of functional measures that indicate tolerance, addiction, diversion, or abuse. AESOP's evidence-based risk-reduction and transparency will benefit physicians, patients, insurers, and state and federal regulators who monitor Schedule II prescribing. And AESOP will be highly valuable to pharmaceutical companies; as the first computerized learning tool for opioid prescribing, AESOP can be play a central role in Risk Management Plans that opioid manufacturers must develop and deploy in order to win FDA approval for any new opioids. Phase I goals include: 1) Clinical research to validate the centerpiece of AESOP, a computer-assisted physician-patient agreement that governs the prescribing relationship and establishes functional goals for the patient, and 2) In-depth interviews with primary care physicians to ensure that the product's design specifications will conform to existing primary care technology and practice infrastructure. Phase II will develop a beta version of AESOP which can be tested and validated in a primary care setting.

Principal Investigator:

Joshua Horwitz
2022990600
JHORWITZ@WATERFORDLS.COM

Business Contact:


2022990600
Small Business Information at Submission:

WATERFORD LIFE SCIENCES
1666 CONNECTICUT AVE, NW, SUITE 500 WASHINGTON, DC 20009

EIN/Tax ID: 943111570
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No