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Enhanced Kidney Dialysis by Ultrasonic Transduction

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29375
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29375
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Wellport, Inc.
3495 Winton Place, Bldg B Rochester, NY 14623
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Enhanced Kidney Dialysis by Ultrasonic Transduction
Agency: HHS
Contract: 1 R43 DK49400-01,
Award Amount: $90,000.00
 

Abstract:

The objective of this research is to improve the efficiency of kidney dialysis. Efficiency of massdetermined by clearance rate across the membrane. One of the primary restrictions to clearance is thcondition at the membrane surface which exists in either tube or channel. The aim is to increase effboundary layer, thus altering clearance of common metabolites such as sodium chloride, urea, creatinWe will create an "active" mixing to increase efficiency by utilizing low power ultrasonic energy toup boundary layers in the blood envelope, allowing more plasma and formed elements to contact membraAn ultrasonic transducer is coupled to parallel plate and hollow fiber dialyzers and then excited wispecific frequency ranges. Improved efficiency is determined by comparison of assay results of bloodfor ultrasonic versus non-ultrasonic (control) dialysis. Additionally, cellular damage is monitoredvalues of ultrasonic versus control dialysis. Coupling ultrasonic transducers to dialyzers should immanagement and reduce costs by diminishing the duration of kidney dialysis treatments.

Principal Investigator:

Stephen Hine
71675

Business Contact:

Small Business Information at Submission:

Wellport, Inc.
3495 Winton Place, Bldg B Rochester, NY 14623

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No