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Company Information:

Name: WESTERN RESEARCH COMPANY, INC.
Address: 3275 W INA RD, STE 215
TUCSON, AZ
Located in HUBZone: No
Woman-Owned: No
Minority-Owned: No
URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $2,761,945.00 39
SBIR Phase II $9,563,606.00 17

Award List:

CCD DIGITIZATION OF ELECTRONHORETIC GELS

Award Year / Program / Phase: 1984 / SBIR / Phase I
Agency: HHS
Principal Investigator: Dr. Brian L. Craine , Senior Scientist
Award Amount: $45,532.00

CCD DIGITIZATION OF ELECTRONHORETIC GELS

Award Year / Program / Phase: 1986 / SBIR / Phase II
Agency: HHS
Principal Investigator: Dr. Brian L. Craine , Senior Scientist
Award Amount: $408,000.00
Abstract:
We propose to develop the application of new two dimensional, state of the art charge coupled device (ccd) image detectors to the problem of analysis of proteins by digitization of two dimensional polyacrylamide electrophoretic gels. long term success of this project will result in commercialization… More

DIGITAL IMAGING COLPOSCOPY

Award Year / Program / Phase: 1986 / SBIR / Phase I
Agency: HHS
Principal Investigator: Dr Brian L Craine , Principal Investigator
Award Amount: $50,000.00

A COMPREHENSIVE SYSTEM FOR DIGITAL FLUORESCEIN ANGIOGRAPHY

Award Year / Program / Phase: 1987 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric r craine phd
Award Amount: $50,000.00
Abstract:
This project will lead to development of a comprehensive system for digital ophthalmological fluorescein angiography.the system is expected to be superior to existing (largely video) systems in several respects: (1) the inclusion of a digital reference library; (2) the maximum efficiency and cost… More

A COST-EFFECTIVE CCD DNA SEQUENCE READER

Award Year / Program / Phase: 1987 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R Craine Phd
Award Amount: $47,000.00

A SYSTEM FOR MACHINE READING OF CHEMICAL SYMBOLS

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
This project will lead to the development of a proof-of-principle system for machine reading and understanding of hardcopy, graphical chemical structures. this research will provide a basis for developing intelligent input devices for entry of chemical structure data into existing and future… More

A COST-EFFECTIVE CCD DNA SEQUENCE READER

Award Year / Program / Phase: 1988 / SBIR / Phase II
Agency: HHS
Principal Investigator: Eric R Craine Phd
Award Amount: $471,000.00
Abstract:
This project will develop the application of state-of-the-art charge-coupled device (ccd) image detectorsto the problem of the automatic analysis of dna-sequencing gels. success of this project will result in commercialization of an instrument capable of reading, interpreting, and storing dna… More

DIGITAL IMAGING COLPOSCOPY

Award Year / Program / Phase: 1989 / SBIR / Phase II
Agency: HHS
Principal Investigator: Dr Brian L Craine , Principal Investigator
Award Amount: $217,000.00
Abstract:
This project will lead th the development of state-of-the- art charge coupled devices (ccd), two dimensional image detector systems suitable for direct retrofit to existing colposcopes of for integration into the design of new colposcopes. success with this project will make possible the… More

ANTIBODY BASED ASSAY FOR QUINOLICIC ACID

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Craine, Brian L , Principal Investigator
Award Amount: $49,877.00
Abstract:
The goal of this phase i project is to prepare antibodies against quinolinic acid and perform some initial experiments to determine the specificity of an assay for quinolinic acid based on these antibodies. the phase i effort will provide an important component of the assay and a clear direction of… More

COMPUTER NAIL BED CAPILLAROSCOPY

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Craine, Brian L , Principal Investigator
Award Amount: $50,000.00
Abstract:
The objective of this project is to construct and evaluate a dedicated computerized digital imaging system for nail bed capillaroscopy that will be useful in the clinical, research and medical education environment. this system will promote more effective use of this diagnostic test through improved… More

VIDEO COMPARATOR FOR ISOLATION OF DERMATOLOGICAL LESIONS

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Craine, Eric R , Principal Investigator
Award Amount: $50,000.00

INFRARED FLUORESCENT GASTROINTESTINAL ENDOSCOPY

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L Craine
Award Amount: $50,000.00
Abstract:
The phase i research project will be a series of proof-of-principle experiments designed to show the feasibility of using infrared florescence to detect blood flow in the submucosa of the human gut. this will be accomplished by retrofitting a sigmoidoscope for imaging in the near ir. the sensitivity… More

SPECTROSCOPIC COLPOSCOPY FOR TISSUE CHARACTERIZATION

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R Craine
Award Amount: $50,000.00
Abstract:
The eventual objective of this project is to make available an innovative new system for use in the noninvasive characterization of cancerous or pre-cancerous tissue on or around the cervix. the goal is to provide earlier detection of disease and consequently better health care for women who are… More

SPECTROSCOPIC SYSTEM FOR DERMATOLOGICAL LESION DIAGNOSIS

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R Craine
Award Amount: $50,000.00
Abstract:
The objective of this program is to make available an innovative new technolgy for characterizing pigmented lesions and other potentially damaged areas of the skin which may be cancerous or pre-cancerous. the goal is to provide a new research and clinical tehnique which can lead to early detection… More

THREE DIMENSIONAL COLPOSCOPIC IMAGING UNIT

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R Craine
Award Amount: $50,000.00

FRACTIONAL UPTAKE (CO) AS AN INDICATOR OF PCP PNEUMONIA

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L Craine
Award Amount: $50,000.00

A SYSTEM FOR COMPUTER-AIDED RIOC EXPERIMENTS

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: John R Engel
Award Amount: $50,000.00

VIDEO COMPARATOR FOR ISOLATION OF DERMATOLOGICAL LESIONS

Award Year / Program / Phase: 1993 / SBIR / Phase II
Agency: HHS
Principal Investigator: Craine, Eric R , Principal Investigator
Award Amount: $500,000.00
Abstract:
This project will result in development and testing of a microcomputer based video image comparator for use in a clinical dermato- logical environment. this device will be used by dermatologists to ease the task of locating new or changed cutaneous lesions which may pose a lethal threat to the… More

FRACTIONAL UPTAKE (CO) AS AN INDICATOR OF PCP PNEUMONIA

Award Year / Program / Phase: 1993 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brian L Craine
Award Amount: $500,000.00
Abstract:
The goal of this project is to test a new prototype, portable carbon monoxide fractional uptake (fu(co)) monitor concept in a clinical environment. the purpose of this monitor is to provide for the early detection of pneumocystis carinii pneumonia (pcp) in a population of aidspatients. in principle,… More

THREE DIMENSIONAL COLPOSCOPIC IMAGING UNIT

Award Year / Program / Phase: 1993 / SBIR / Phase II
Agency: HHS
Principal Investigator: Eric R Craine
Award Amount: $500,000.00
Abstract:
The objective of this project is to develop a clip-on device for structured light pattern projections to be used with colposcopes, along with a software upgrade for digital imaging colposcopes. this system will allow the user to recover three dimensional topographic data from colposcopic images of… More

Video Image Processing for Laparoscopic Surgery

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $50,000.00
Abstract:
The goal is to develop a specific software and hardware system that will integrate with current video Laparoscopic surgical devices and provide for improved recognition and identification of relevant anatomical structures. In Phase I, we will characterize the color properties of key anatomical… More

Software for Early Detection of Carpal Tunnel Syndrome

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: John R. Engel
Award Amount: $50,000.00
Abstract:
The goal is to develop a software product which can indicate the onset of carpal tunnel syndrome (CTS) in computer keyboard operators. This software will apply pattern analysis methods to keystroke time series data acquired during normal typing at a microcomputer keyboard. The specific Phase I… More

Cervical Cancer Screening by Enhanced Direct Inspection

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $50,000.00
Abstract:
The goal is to develop an improved vaginal speculum that will incorporate a magnifying lens permitting a more detailed inspection of the cervix during routine pelvic exams. This improved speculum will potentially have a significant impact on reducing the number of false negative cervical cancer… More

Solid-State Photon Counting Imager

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith Hege
Award Amount: $50,000.00
Abstract:
The goal of this research project is to explore the feasibility of developing a powerful new visible light imaging array for use in a camera system and potentially applicable to a variety of medical and biotechnology uses. This innovative imaging technology involves use of Visible Light Photon… More

Knowledge-Based Chemical Symbol Recognition System

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: John R. Engel
Award Amount: $50,000.00
Abstract:
The ultimate goal is to develop and commercialize a functional, low-cost system for machine reading and recognition of chemical structure diagrams. The specific Phase I goal is to demonstrate the feasibility of developing such a system by using a knowledge-based approach which provides a logical… More

Training Simulator for Video Laparoscopic Surgery

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $50,000.00

A SYSTEM FOR COMPUTER-AIDED RIOC EXPERIMENTS

Award Year / Program / Phase: 1994 / SBIR / Phase II
Agency: HHS
Principal Investigator: John R Engel
Award Amount: $485,560.00
Abstract:
The goal of this project is to devleop an easy-to-use, microcomputer-based system for facilitating the design, implementation and analysis of receiver operating characteristic (roc) experiments. the specific phase i goal is to demonstrate the feasibility of developing such a system by specifying the… More

Classifying Cervix Tissue Patterns with Texture Analysis

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: HHS
Principal Investigator: Qiang Ji
Award Amount: $71,841.00
Abstract:
The high false-negative rate from Papanicolaou (Pap) smears has motivated the use ofcolposcopy to perform visual inspection of the uterine cervix. It has made a tremendous impact on theability of physicians to perform accurate punch biopsies for histological analysis. However, the difficultyin… More

Conditional Mutants of Streptavidin

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian Craine
Award Amount: $100,000.00
Abstract:
We will isolate a temperature sensitive mutant of streptavidin that will bind biotin at 4C but notbe accomplished by chemical mutagenesis to saturate the streptavidin gene with mutations. A scheme ftemperature sensitive mutant will be employed. The library of mutants and the enriched library… More

HOME BASED SKIN CANCER SCREENING AID

Award Year / Program / Phase: 1996 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $96,410.00

Training Simulator for Video Laparoscopic Surgery

Award Year / Program / Phase: 1997 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $176,288.00
Abstract:
The goal is to develop a video based simulator for the training of necessary hand-eye coordination skills for the performance of video laparoscopic surgery. The training simulator will be connected to a microcomputer which will prompt the student to perform particular tasks using surgical… More

DIAGNOSTIC TEST FOR IRRITABLE BOWEL SYNDROME

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Craine, brian l
Award Amount: $99,960.00

HOME BASED SKIN CANCER SCREENING AID

Award Year / Program / Phase: 1997 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $534,402.00

NONINVASIVE DERMATOLOGICAL LESION CLASSIFIER

Award Year / Program / Phase: 1998 / SBIR / Phase I
Agency: HHS
Principal Investigator: Craine, Eric R
Award Amount: $100,000.00

DIAGNOSTIC TEST FOR IRRITABLE BOWEL SYNDROME

Award Year / Program / Phase: 1998 / SBIR / Phase II
Agency: HHS
Principal Investigator: Craine, brian l
Award Amount: $746,571.00

SIMPLE LAB TEST FOR LOCALIZING GI BLEEDING SITE

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $97,759.00
Abstract:
Not Available Field detection of multiple biological agents based on rapid nucleic acid amplification is an anticipated goal of DOD We here propose development of a hand held battery operated microfluorimeter device for fluorescence based detect ion and quantitation of biological agent a after… More

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $96,972.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $99,850.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R. Craine
Award Amount: $0.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase II
Agency: HHS
Principal Investigator: Eric R. Craine
Award Amount: $363,073.00

NONINVASIVE TEST FOR MANAGEMENT OF NONULCER DYSPEPSIA

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $0.00
Abstract:
Nonulcer dyspepsia is a highly prevalent medical condition affecting up to 30 percent of the Western population, accounting for 2-5 percent of all visits to primary care physicians and leads to over one billion dollars worth of upper endoscopy procedures per year. In an attempt to lower this… More

NONINVASIVE TEST FOR MANAGEMENT OF NONULCER DYSPEPSIA

Award Year / Program / Phase: 2002 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $749,383.00
Abstract:
Nonulcer dyspepsia is a highly prevalent medical condition affecting up to 30 percent of the Western population, accounting for 2-5 percent of all visits to primary care physicians and leads to over one billion dollars worth of upper endoscopy procedures per year. In an attempt to lower this… More

SIMPLE LAB TEST FOR LOCALIZING GI BLEEDING SITE

Award Year / Program / Phase: 2002 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $947,393.00
Abstract:
Bleeding in the gastrointestinal tract is a major clinical problem. Bleeding may be acute and severe or it may be chronic and unnoticed (i.e. occult bleeding). The acute bleeding is a medical emergency that needs to be evaluated and treated immediately. Occult bleeding may be a sign of colon cancer… More

QUALITY CONTROL TOOL FOR NEWBORN SCREENING BLOOD SAMPLES

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $0.00
Abstract:
DESCRIPTION (provided by applicant): Essentially all newborns in the United States (about 4 million per year) and at least 30 other countries have blood samples obtained on filter paper cards for the purpose of screening for a number of metabolic and genetic diseases. To prevent morbidity, such as… More

SIMPLE LAB TEST FOR LOCALIZING GI BLEEDING SITE

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $0.00
Abstract:
Bleeding in the gastrointestinal tract is a major clinical problem. Bleeding may be acute and severe or it may be chronic and unnoticed (i.e. occult bleeding). The acute bleeding is a medical emergency that needs to be evaluated and treated immediately. Occult bleeding may be a sign of colon cancer… More

All Digital Home Use System for Mole Monitoring

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R. Craine
Award Amount: $69,956.00
Abstract:
DESCRIPTION (provided by applicant): The incidence of skin cancer and melanoma continues to rise rapidly in the United States. The best defense against often-fatal melanoma is early detection of the disease, a task that is aided by early detection of new or changed pigmented moles. The medical… More

Noninvasive Home Monitor for Sleep Apnea Testing

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $100,000.00
Abstract:
DESCRIPTION (provided by applicant): Obstructive sleep apnea affects about 3-4% of the population including children. There is considerable associated morbidity and mortality. In particular there is a strong association with hypertension and cardiac disease. Daytime somnolence leads to increased… More

Cell Collection Device for Colon Cancer Screening

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $103,288.00
Abstract:
DESCRIPTION (provided by applicant): The long term goal of this project is to develop a simple to use device for sampling cells along the length of the colon for purposes of screening for colorectal cancer. This device is intended to be used to provide cell samples for use in current and future DNA… More

QUALITY CONTROL TOOL FOR NEWBORN SCREENING BLOOD SAMPLES

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $539,545.00
Abstract:
DESCRIPTION (provided by applicant): Essentially all newborns in the United States (about 4 million per year) and at least 30 other countries have blood samples obtained on filter paper cards for the purpose of screening for a number of metabolic and genet ic diseases. To prevent morbidity, such as… More

Alcohol Effects Simulator for Pilot Training

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R. Craine
Award Amount: $114,513.00
Abstract:
DESCRIPTION (provided by applicant): This proposal is a direct response to an NIH-stated need for a system to simulate piloting aircraft under hypothetical or actual drinking handicaps and designed to predict fatal and nonfatal accident involvement . This requirement, released by the National… More

Noninvasive Home Monitor for Sleep Apnea Testing

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $738,025.00
Abstract:
DESCRIPTION (provided by applicant): Obstructive sleep apnea affects about 3-4% of the population including children. There is considerable associated morbidity and mortality. In particular there is a strong association with hypertension and cardiac diseas e. Daytime somnolence leads to increased… More

Novel Respiratory Rate Monitor for Routine Use

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $101,957.00
Abstract:
DESCRIPTION (provided by applicant): The goal of this project is to develop an automated respiratory rate monitor that is economical, easy to use, accurate and widely accessible. The motivation for this project is well documented findings that respiratory rates are not accurately measured in many… More

Alcohol Effects Simulator for Pilot Training

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: HHS
Principal Investigator: Eric R. Craine
Award Amount: $721,058.00
Abstract:
DESCRIPTION (provided by applicant): This proposal is a direct response to an NIH-stated requirement for a system to simulate piloting aircraft under hypothetical or actual drinking handicaps . This requirement, released by the National Institute of Alcoh ol Abuse and Alcoholism, recognizes that… More

Non-prescription Drug Training for Pilots

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R. Craine
Award Amount: $118,088.00
Abstract:
DESCRIPTION (provided by applicant): This proposal is a direct response to a stated need for a system to ....educate and alert aviators during their flight training and medical examinations, with real-life examples of the adverse effects of antihistamine s (and over-the-counter-drugs) and… More

Novel Respiratory Rate Monitor for Routine Use

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brian L. Craine
Award Amount: $966,308.00
Abstract:
DESCRIPTION (provided by applicant): The goal of this project is to develop an automated respiratory rate monitor that is economical, easy to use, accurate and widely accessible. The motivation for this project is well documented findings that respiratory rates are not accurately measured in many… More

Community Oriented Tool for Reducing Melanoma Health Disparities

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Eric R. Craine – 520-325-4505
Award Amount: $398,942.00
Abstract:
DESCRIPTION (provided by applicant): Melanoma is a frequently fatal cancer that, if detected early, is relatively easily cured. This disease is rapidly increasing in frequency and has recently been identified by the National Center for Health Statistics Health Disparities Study as a high profile… More