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Conditional Mutants of Streptavidin

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29246
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29246
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
WESTERN RESEARCH COMPANY, INC.
3275 W INA RD, STE 215 TUCSON, AZ -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Conditional Mutants of Streptavidin
Agency: HHS
Contract: 1 R43 CA68821-01,
Award Amount: $100,000.00
 

Abstract:

We will isolate a temperature sensitive mutant of streptavidin that will bind biotin at 4C but notbe accomplished by chemical mutagenesis to saturate the streptavidin gene with mutations. A scheme ftemperature sensitive mutant will be employed. The library of mutants and the enriched library willcomputer assisted system for colony screening to find candidate mutants. These mutants will be chararesulting mutants are expected to provide a valuable and novel addition to avidin-biotin technology.

Principal Investigator:

Brian Craine
60225

Business Contact:

Small Business Information at Submission:

Western Research Company, Inc.
2127 E Speedway, Suite 209 Tucson, AZ 85719

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No