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AN EXTRACORPOREAL PULSATILE ASSIST DEVICE (EPAD)

Award Information

Agency:
Department of Health and Human Services 		Branch:
N/A 		Award ID:
5007 		Program Year/Program:
1988 / SBIR
Agency Tracking Number:
5007 		Solicitation Year:
N/A 		Solicitation Topic Code:
N/A 		Solicitation Number:
N/A
Small Business Information
WHALEN BIOMEDICAL, INC
11 MILLER ST SOMERVILLE, MA 02143-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1988
Title: AN EXTRACORPOREAL PULSATILE ASSIST DEVICE (EPAD)
Agency: HHS
Contract: N/A
Award Amount: $500,000.00
 

Abstract:

THE OBJECTIVE OF THIS PROGRAM IS THE DEVELOPMENT OF AN EXTRACORPOREAL PULSATILE ASSIST DEVICE (EPAD), A VALVELESS DIASTOLIC AUGMENTATION PUMP WITH VARIABLE STROKE VOLUMES UP TO 80 ML PER BEAT. THE EPAD IS DESIGNED AS A LOW-COST, DISPOSABLE DEVICE WHOSE INITIAL APPLICATION WILL BE AS A TEMPORARY RIGHT VENTRICULAR ASSIST DEVICE IN CONJUNCTION WITH THE USE OF A LEFT VENTRICULAR ASSIST DEVICE (LVAD) FOR PATIENTS IN REVERSIBLE BIVENTRICULAR FAILURE. THE EPAD WILLALSO BE USABLE ULTIMATELY AS A TEMPORARY LEFT HEART ASSIST DEVICE WHICH, IN CONTRAST TO THE INTRA-AORTIC BALLOON PUMP (IAPB), PROVIDES ANY DESIRED STROKE VOLUME AND DELIVERS ITS OUTPUT INTO THE ASCENDING AORTA FOR MAXIMAL EFFECTIVENESS. THE EPAD DESIGN PERMITS RAPID OPEN-CHEST CANNULATION OF EITHER THE PULMONARY ARTERY OR AORTA WITHOUT THE NEED FOR ANEND-TO-SIDE ANASTOMOSIS OF A VASCULAR GRAFT FOR BLOOD ACCESS. BECAUSE THE DEVICE IS READILY MANUFACTURABLE AND USES SIMPLE MOLDED COMPONENTS, IT IS LIKELY TO BE COST- COMPETITIVE WITH THE IAPB WHEN PRODUCED IN QUANTITY. PHASE I DEVELOPMENT WILL CONSIST OF PROTOTYPE FABRICATION AND IN VITRO CHARACTERIZATION, FOLLOWED BY A SERIES OF ACUTE IN VIVO STUDIES USING THE EPAD AS A RIGHT HEART ASSIST DEVICE WITH A MODEL OF INDUCED RIGHT VENTRICULAR FAILURE.

Principal Investigator:

Robert L Whalen
Principal Investigator
6176613693

Business Contact:

Small Business Information at Submission:

Whalen Biomedical Inc.
5 Howland Street Cambridge, MA 02138

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No