Not Available Under this Phase I SBIR program, ORINCON proposes to develop and demonstrate digital signal processing (DSP) algorithms to provide substantial improvements in the identification and quantification of chemical compounds using Fourier Transform Infrared (FTIR) Spectroscopy. The… More

Not Available When aircraft operate with effectors at their rate or position limit, the control loop is opened and a number of problems can occur ranging from performance degradation to loss of stability. For this reason, most modern control laws are designed to avoid

DESCRIPTION (provided by applicant)Advances in large-scale production of mammalian cells or their secreted proteins have led to the licensure of many therapeutic and diagnostic products. Culture devices, such as stirred-tank and hollow fiber bioreactors, have utility in large-scale production, but… More

DESCRIPTION (provided by applicant)Advances in large-scale production of mammalian cells or their secreted proteins have led to the licensure of many therapeutic and diagnostic products. Culture devices, such as stirred-tank and hollow fiber bioreactors, have utility in large-scale production, but… More

DESCRIPTION (provided by applicant): The culture of cells is currently undertaken to produce small and large quantities of cells and cell-secreted products, such as growth factors, enzymes, hormones, monoclonal antibodies, interferons, interleukins, vaccines, diagnostics, and viral vectors. A… More

DESCRIPTION (provided by applicant): The culture of cells is currently undertaken to produce small and large quantities of cells and cell-secreted products, such as growth factors, enzymes, hormones, monoclonal antibodies, interferons, interleukins, vaccines, diagnostics, and viral vectors. A… More

DESCRIPTION (provided by applicant): There exists a need for a single device that can culture, ship, and infuse islet. Flasks and petri dishes are the devices currently used to store islets. They are a weak link in the process because these devices have inherent design limitations that do not… More

DESCRIPTION (provided by applicant): There is an existing need for more efficient cell culture devices that retain the simplicity of traditional devices such as flasks and roller bottles. Approval of this grant will initiate the investigation of a low profile static cell culture device (LPD) that is… More

DESCRIPTION (provided by applicant): The culture and shipment of islets are an integral part of islet transplant research. Flasks, petri dishes, and bags are the devices used to perform that role. However, these devices have inherent design characteristics that make them poorly suited to the unique… More

DESCRIPTION (provided by applicant): For much of the small and mid-scale cell culture work at the core of biotechnology, traditional culture ware such as flasks and roller bottles are the only devices that are practical for use. Although they are easy to u se and disposable, they have design limits… More

DESCRIPTION (provided by applicant): The Field: The most effective treatment for metastatic melanoma is Tumor Infiltrating Lymphocyte (TIL) therapy, in which TILs are obtained from a patient's tumor fragments, grown to an immense quantity in vitro, and infused back into the patient (1-4). The… More