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Company Information:

Company Name:
X-RAY OPTICAL SYSTEMS, INC.
Address:
15 Tech Valley Drive
East Greenbush, NY 12061-4134
Phone:
(518) 880-1500
URL:
N/A
EIN:
223072722
DUNS:
780681938
Number of Employees:
80
Woman-Owned?:
No
Minority-Owned?:
No
HUBZone-Owned?:
No

Commercialization:

Has been acquired/merged with?:
N/A
Has had Spin-off?:
N/A
Has Had IPO?:
N/A
Year of IPO:
N/A
Has Patents?:
N/A
Number of Patents:
N/A
Total Sales to Date $:
$ 0.00
Total Investment to Date $
$ 0.00
POC Title:
N/A
POC Name:
N/A
POC Phone:
N/A
POC Email:
N/A
Narrative:
N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $4,111,957.00 56
SBIR Phase II $16,746,191.00 26

Award List:

USE OF A KUMAKHOV LENS WITH SYNCHROTRON X-RAYS TO ENHANCE MEDICAL IMAGING TECHNIQUES

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$46,332.00
Agency:
DOE
Principal Investigator:
Igor Y Ponomarev , Principal Investigator
Abstract:
The objective of this project is to examine the feasibility of using kumakhov lenses to enhance the performance of medical imaging techniques using synchrotron x-rays. kumakhov lenses are bundles of fibers that conduct x-rays through channeling similar to the way fiber optics conduct visible… More

A KUMAKHOV LENS WITH A ROTATING ANODE TO OBTAIN AN X-RAY SOURCE, AS AN ADVANTAGEOUS ALTERNATIVE TO SYNCHROTRONS

Award Year / Program / Phase:
1991 / SBIR / Phase I
Award Amount:
$47,603.00
Agency:
DOE
Principal Investigator:
Aleksandr I Kolomijtsev , Principal Investigator
Abstract:
N/a

A KUMAKHOV LENS WITH A ROTATING ANODE TO OBTAIN AN X-RAY SOURCE, AS AN ADVANTAGEOUS ALTERNATIVE TO SYNCHROTRONS

Award Year / Program / Phase:
1992 / SBIR / Phase II
Award Amount:
$496,255.00
Agency:
DOE
Principal Investigator:
Aleksandr I Kolomijtsev , Principal Investigator
Abstract:
Measurements and calculations made in the soviet union indicate the possibility of using a new capillary-based x-ray optical system to increase the intensity and decrease the divergence of laboratory x-ray sources sufficiently for them to compete with, and in some cases even surpass, synchrotron… More

NEUTRON FOCUSING USING KUMARKHOV LENS

Award Year / Program / Phase:
1992 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
NSF
Principal Investigator:
Vasili Sharov
Abstract:
Characterization of modern materials requires analytical probes with superior detection limits and spatial resolutionon a submicron scale. we propose to develop a neutron focusing device which can significantly enhance analytical techniques used for the nondestructive investigation of surfaces,… More

IMPROVED MAMMOGRAPHIC IMAGING WITH CAPILLARY OPTICS

Award Year / Program / Phase:
1992 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Qi-fan Xiao
Abstract:
The quality of conventional mammograms is limited in contrast by the large fraction of scattered photons and the low inherent contrast of the tissues of the breast, and in resolution by geometric unsharpness determined by finite x-ray focal spot size. better system resolution and contrast will allow… More

A COLD/THERMAL BEAM BENDER USING CAPILLARY OPTICS TO INCREASE THE NUMBER OF END-GUIDE INSTRUMENT POSITIONS

Award Year / Program / Phase:
1992 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
DOE
Principal Investigator:
Abstract:
N/a

A COLD/THERMAL BEAM BENDER USING CAPILLARY OPTICS TO INCREASE THE NUMBER OF END-GUIDE INSTRUMENT POSITIONS

Award Year / Program / Phase:
1993 / SBIR / Phase II
Award Amount:
$474,458.00
Agency:
DOE
Principal Investigator:
Abstract:
The development and use of nondestructive, neutron-based analytical techniques for materials characterization-including neutron-scattering applications using cold and thermal neutrons-have been hindered by limited access to high flux sources of low energy neutrons. this project is developing a… More

ONE-PIECE KUMAKHOV OPTICS TO ACHIEVE INCREASED CONTROL OF X-RAY AND NEUTRON BEAMS

Award Year / Program / Phase:
1993 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
NSF
Principal Investigator:
Qo-fan Xiao
Abstract:
Capillary-based optics (kumakhov optics) control x-ray and low-energy neutron beams by means of multiple reflections at less than the critical angle. optics have demonstrated the capability to form convergent or quasi-parallel beams. such controlled beams have applications in many x-ray an neutron… More

Kumakhow Optics for Clinical Dual-Energy Angiography

Award Year / Program / Phase:
1993 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Qi-Fan Xiao
Abstract:
Conventional coronary angiography requires cardiac catheterization to inject an iodine contrast agent. If dual-energy digital subtraction angiography could be performed in clinical practice using intravenous iodine injections, patient risk could be substantially reduced. Additionally, x-ray exposure… More

Integrated CAD/CAM Process for Cost-Effective Flexible Manufacturing

Award Year / Program / Phase:
1993 / SBIR / Phase I
Award Amount:
$54,233.00
Agency / Branch:
DOD / DARPA
Principal Investigator:
Michael Vartanian
Abstract:
N/a

Capillary Optics to Control Neutrons for BNCT

Award Year / Program / Phase:
1994 / SBIR / Phase I
Award Amount:
$73,739.00
Agency:
HHS
Principal Investigator:
Qi-Fan Xiao
Abstract:
Boron Neutron Capture Therapy is a two component modality. It is based on selective deliveryof a boronated pharmaceutical to cancerous tissue, followed by irradiation with thermal neutrons andsubsequently captured by the boron nuclei. A collaborative effort will be undertaken to develop aneutron gun… More

Neutron Absorption Techniques Using Focused Cold Neutrons From a Radioisotopic-Source Capillary-Optic Syst

Award Year / Program / Phase:
1995 / SBIR / Phase I
Award Amount:
$62,199.00
Agency:
NSF
Principal Investigator:
Vasily Sharov
Abstract:
N/a

Monolithic Polycapillary Optic for Bending and Microfocusing Neutron Beams

Award Year / Program / Phase:
1996 / SBIR / Phase I
Award Amount:
$73,429.00
Agency:
DOE
Principal Investigator:
Mr. Igor Ponomarev , Researcher
Abstract:
41315 November 21, 1996 X-ray Optical Systems, Inc. Neutron analyses are in great demand because of the unique information obtained through the characterization of materials using the properties of neutrons. However, material analysis using neutron beam… More

Coating Capillary Optics to Improve X-ray and Neutron Transmission

Award Year / Program / Phase:
1996 / SBIR / Phase I
Award Amount:
$75,000.00
Agency:
DOE
Principal Investigator:
Dr. R. Gregory Downing
Abstract:
41316 November 22, 1996 X-Ray Optical Systems, Inc. Because of their recently demonstrated ability to provide significant improvements in beam intensity, capillary optics are finding use for controlling x rays and neutrons across a wide range of fields. … More

SBIR Phase I: Light Element X-Ray Flourescence Using Capillary X-Ray Optics

Award Year / Program / Phase:
1996 / SBIR / Phase I
Award Amount:
$72,356.00
Agency:
NSF
Principal Investigator:
Qi-Fan Xiao
Abstract:
N/a

Cold Neutron Microprobe for Material Analysis Using Tapered Capillary Optics

Award Year / Program / Phase:
1996 / SBIR / Phase I
Award Amount:
$49,966.00
Agency:
DOC
Principal Investigator:
Vasily Sharov , Principal Investigator
Abstract:
N/a

SBIR PHASE I: Monolothic Capillary Optics for Protein Crystallography with Laboratory X-Ray Sources

Award Year / Program / Phase:
1996 / SBIR / Phase I
Award Amount:
$74,596.00
Agency:
NSF
Principal Investigator:
Johannes Ullrich
Abstract:
N/a

Integrated CAD/CAM Process for Cost-Effective Flexible Manufacturing

Award Year / Program / Phase:
1997 / SBIR / Phase II
Award Amount:
$704,097.00
Agency / Branch:
DOD / DARPA
Principal Investigator:
Michael Vartanian
Abstract:
Although x-ray photoelectron spectroscopy (CPS) is an extremely valuable analytical tool for material characterization in semiconductor manufacturing, its use is limited by the currently available spatial resolution. The economical fabrication of ULSI circuits depends on in-situ non-destructive… More

Cold Neutron Microprobe for Material Analysis Using Tapered Capillary Optics

Award Year / Program / Phase:
1997 / SBIR / Phase II
Award Amount:
$197,275.00
Agency:
DOC
Principal Investigator:
Vasily Sharov , Principal Investigator
Abstract:
The project will research a new generation of optic for focusing cold neutrons using tapered capillary optics. The success of the program will result in neutron beam probes with unprecedented spatial resolution and detection limits for small sample volumes. The individuals involved are the world… More

Integrated CAD/CAM Process for Cost-Effective Flexible Manufacturing of High-Performance X-ray Optics

Award Year / Program / Phase:
1997 / SBIR / Phase II
Award Amount:
$704,097.00
Agency / Branch:
DOD / ARMY
Principal Investigator:
R. Gregory Downing
Abstract:
Polycapillary x-ray monolithic optics have the potential to be one of the best methods for controlling x-ray beams across a broad energy spectrum because of their efficiency, size, and applicability to a variety of technologies. Widespread use of polycapillary optics is currently impeded because… More

SBIR Phase I: Light Element X-Ray Flourescence Using Capillary X-Ray Optics

Award Year / Program / Phase:
1997 / SBIR / Phase II
Award Amount:
$299,281.00
Agency:
NSF
Principal Investigator:
Qi-Fan Xiao
Abstract:
N/a

Low Power X-Ray Diffraction Unit For Planetary Landers

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$67,888.00
Agency:
NASA
Principal Investigator:
Johannes Ullrich , RESEARCHER
Abstract:
N/a

Integrated CAD/CAM Process for Cost-Effective Flexible Manufacturing of High-Performance X-ray Optics

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$145,000.00
Agency / Branch:
DOD / ARMY
Principal Investigator:
R. Gregory Downing
Abstract:
N/a

Hard X-Ray Polycapillary Optics To Provide A High-Efficiency Broad-Band Concentrator In The Spectral Range Of 10 Kev To

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$69,717.00
Agency:
NASA
Principal Investigator:
Igor Ponomarev , RESEARCH SCIENTIST
Abstract:
N/a

SBIR Phase I: High-Intensity Microfocus X-Ray Fluorescence Using Monolithic Capillary Optics

Award Year / Program / Phase:
1997 / SBIR / Phase I
Award Amount:
$75,000.00
Agency:
NSF
Principal Investigator:
R. Gregory Downing
Abstract:
N/a

Low Power X-Ray Diffraction Unit For Planetary Landers

Award Year / Program / Phase:
1998 / SBIR / Phase II
Award Amount:
$393,933.00
Agency:
NASA
Principal Investigator:
Johannes Ullrich , RESEARCHER
Abstract:
N/a

High-Intensity Microfocus X-Ray Fluorescence Using Monolithic Capillary Optics

Award Year / Program / Phase:
1998 / SBIR / Phase II
Award Amount:
$384,228.00
Agency:
NSF
Principal Investigator:
R. Gregory Downing
Abstract:
N/a

N/A

Award Year / Program / Phase:
1999 / SBIR / Phase I
Award Amount:
$0.00
Agency:
HHS
Principal Investigator:
Abstract:
N/a

N/A

Award Year / Program / Phase:
1999 / SBIR / Phase II
Award Amount:
$816,705.00
Agency:
HHS
Principal Investigator:
Abstract:
N/a

Portable Parallel Beam X-Ray Diffraction System for In-Line Process Control in the Steel Industry

Award Year / Program / Phase:
1999 / SBIR / Phase I
Award Amount:
$99,861.00
Agency:
DOE
Principal Investigator:
Abstract:
Not Available There is a need for satellite position determination during launch and in orbit. During different phases of operation the satellite could be spinning up to 60 revolutions per minute and spin axis tumbling. The satellite position can be determined by an onboard GPS receiver that… More

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$127,223.00
Agency:
HHS
Principal Investigator:
Zewu Chen
Abstract:
Not Available This Phase 1 SBIR proposal details an approach to equipment health monitoring which is able to diagnose a specific failure without an analytic model, and without data obtained for specific failure cases. It is quite common to add sensors to electromechan

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$74,948.00
Agency:
DOC
Principal Investigator:
Ning Gao, Research Scientist
Abstract:
N/a

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$99,563.00
Agency:
DOE
Principal Investigator:
Ning Gao, Research Scientist
Abstract:
N/a

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$99,369.00
Agency:
DOE
Principal Investigator:
Michele McColgan, Research Scientist
Abstract:
N/a

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$97,505.00
Agency:
NSF
Principal Investigator:
Zewu Chen
Abstract:
N/a

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$99,811.00
Agency:
HHS
Principal Investigator:
Zewu Chen
Abstract:
N/a

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$0.00
Agency:
DOE
Principal Investigator:
Michael Haller, Applications Engineer
Abstract:
N/a

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase II
Award Amount:
$749,831.00
Agency:
DOE
Principal Investigator:
Michael Haller, Applications Engineer
Abstract:
N/a

N/A

Award Year / Program / Phase:
2000 / SBIR / Phase I
Award Amount:
$99,289.00
Agency:
NSF
Principal Investigator:
Ning Gao
Abstract:
N/a

N/A

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$0.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase II project will meet the demand from the microelectronics industry for an improved micro x-ray fluorescence instrument for thin film measurements. A new technique, monochromatic micro x-ray fluorescence (MMXRF) analysis using doubly curved crystal… More

N/A

Award Year / Program / Phase:
2001 / SBIR / Phase II
Award Amount:
$496,758.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase II project will meet the demand from the microelectronics industry for an improved micro x-ray fluorescence instrument for thin film measurements. A new technique, monochromatic micro x-ray fluorescence (MMXRF) analysis using doubly curved crystal… More

N/A

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$94,318.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase I project will address improved wafer contamination analysis in the microelectronics industry. Phase I will examine a new technique called focused beam total reflection x-ray fluorescence (TXRF). Based on point-focusing toroidal crystal optics,… More

Compact Polycapillary-Based Microbeam X-Ray Fluorecence Analysis System for Remote Monitoring of Metal Contamination

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$0.00
Agency:
DOE
Principal Investigator:
Ning Gao, Research Scientist
Abstract:
60740 Conventional X-ray Fluorescence (XRF) analysis, used in DOE environmental management operations, is usually performed off-site and cannot provide sufficient detection sensitivity for certain types of materials. In-situ applications are difficult because such systems are bulky,… More

Compact Polycapillary-Based Microbeam X-Ray Fluorecence Analysis System for Remote Monitoring of Metal Contamination

Award Year / Program / Phase:
2001 / SBIR / Phase II
Award Amount:
$749,921.00
Agency:
DOE
Principal Investigator:
Ning Gao, Research Scientist
Abstract:
60740 Conventional X-ray Fluorescence (XRF) analysis, used in DOE environmental management operations, is usually performed off-site and cannot provide sufficient detection sensitivity for certain types of materials. In-situ applications are difficult because such systems are bulky,… More

N/A

Award Year / Program / Phase:
2001 / SBIR / Phase II
Award Amount:
$276,825.00
Agency:
DOC
Principal Investigator:
Ning Gao, Research Scientist
Abstract:
This SBIR Phase II project will significantly improve the quality of elemental analysis in SEMS under partial pressure conditions by using a polycapillary x-ray optic in front of the energy dispersive spectrometer (EDS) in low-vacuum scanning electron microscopes (LV-SEM) or environmental SEMs… More

N/A

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$0.00
Agency:
DOC
Principal Investigator:
Ning Gao, Research Scientist
Abstract:
This SBIR Phase II project will significantly improve the quality of elemental analysis in SEMS under partial pressure conditions by using a polycapillary x-ray optic in front of the energy dispersive spectrometer (EDS) in low-vacuum scanning electron microscopes (LV-SEM) or environmental SEMs… More

SBIR Phase II: Focused Beam Total Reflection X-Ray Fluorescence Analysis Using Doubly-Curved Crystals

Award Year / Program / Phase:
2002 / SBIR / Phase II
Award Amount:
$499,864.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase II project proposes to meet the demand from the microelectronics industry for improved wafer contamination analysis. Wafer contamination control is critical for Ultra Large Scale Integrated (ULSI) technology and there is a strong demand for a… More

SBIR Phase II: Focused Beam Total Reflection X-Ray Fluorescence Analysis Using Doubly-Curved Crystals

Award Year / Program / Phase:
2002 / SBIR / Phase I
Award Amount:
$0.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase II project proposes to meet the demand from the microelectronics industry for improved wafer contamination analysis. Wafer contamination control is critical for Ultra Large Scale Integrated (ULSI) technology and there is a strong demand for a… More

SBIR Phase I: New Convergent X-Ray Beam Based System for Protein Crystallography

Award Year / Program / Phase:
2002 / SBIR / Phase I
Award Amount:
$99,934.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovative Research Phase I project proposesto develop a new approach to protein x-ray crystallography using convergent beams. This new technology is based on the development of convergent beam x-ray optics and of protein diffraction theory with 2-dimensional convergent x-ray… More

LOW LEVEL TRACES MAPPING USING MONOCHROMATIC X-RAYS

Award Year / Program / Phase:
2002 / SBIR / Phase I
Award Amount:
$0.00
Agency:
HHS
Principal Investigator:
Abstract:
There are important medical applications that will benefit from a desktop imaging tool which detects and maps parts per billion level metals and other heavy elements in tissues in vitro and in vivo. A compact instrument will be proposed for elemental imaging of dry tissues as well as living tissues… More

LOW LEVEL TRACES MAPPING USING MONOCHROMATIC X-RAYS

Award Year / Program / Phase:
2002 / SBIR / Phase II
Award Amount:
$646,745.00
Agency:
HHS
Principal Investigator:
Abstract:
There are important medical applications that will benefit from a desktop imaging tool which detects and maps parts per billion level metals and other heavy elements in tissues in vitro and in vivo. A compact instrument will be proposed for elemental imaging of dry tissues as well as living tissues… More

Using Convergent Beams for Small-Sample, Time-of-Flight Neutron Diffraction

Award Year / Program / Phase:
2002 / SBIR / Phase I
Award Amount:
$98,713.00
Agency:
DOE
Principal Investigator:
Abstract:
70146 Currently, large crystals and long measurement times are required for neutron diffraction measurements, used in materials science research. The use of convergent beam diffraction could significantly reduce both crystal size and measurement time for otherwise impractical neutron… More

OXIDATION STATE DETERMINATION IN CHROMIUM CARCINOGENESIS

Award Year / Program / Phase:
2002 / SBIR / Phase I
Award Amount:
$0.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): Some chromium (VI) compounds are documented human propose measuring the intracellular oxidation state of Cr carcinogens, but the exact mechanism of Cr induced cancer is unknown. Oxidation state determination of intracellular Cr will provide important information… More

OXIDATION STATE DETERMINATION IN CHROMIUM CARCINOGENESIS

Award Year / Program / Phase:
2002 / SBIR / Phase II
Award Amount:
$950,261.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): Some chromium (VI) compounds are documented human propose measuring the intracellular oxidation state of Cr carcinogens, but the exact mechanism of Cr induced cancer is unknown. Oxidation state determination of intracellular Cr will provide important information… More

Using Convergent Beams for Small-Sample, Time-of-Flight Neutron Diffraction

Award Year / Program / Phase:
2003 / SBIR / Phase II
Award Amount:
$695,998.00
Agency:
DOE
Principal Investigator:
Abstract:
70146S02-II Neutron diffraction is an important tool for the structural analysis of molecules. However, limitations on available beam intensities can lead to long or even impractical measurement times when only small samples are available. This project will develop technology for focusing… More

Using Convergent Beams for Small-Sample, Time-of-Flight Neutron Diffraction

Award Year / Program / Phase:
2003 / SBIR / Phase I
Award Amount:
$0.00
Agency:
DOE
Principal Investigator:
Abstract:
70146S02-II Neutron diffraction is an important tool for the structural analysis of molecules. However, limitations on available beam intensities can lead to long or even impractical measurement times when only small samples are available. This project will develop technology for focusing… More

SBIR Phase I: Development of a Hybrid Optic for Proximity X-Ray Lithography

Award Year / Program / Phase:
2003 / SBIR / Phase I
Award Amount:
$99,971.00
Agency:
NSF
Principal Investigator:
Huapeng Huang
Abstract:
This SBIR Phase I project will determine the feasibility of a hybrid reflector/polycapillary collimating optic to produce an intense and uniform x-ray beam at least 50x50 mm2 in cross a sectional area from a high-intensity laser plasma x-ray source. An all polycapillary collimator has been shown to… More

SBIR Phase I: A Compact Micro X-Ray Absorption Spectrometer System

Award Year / Program / Phase:
2003 / SBIR / Phase I
Award Amount:
$99,995.00
Agency:
NSF
Principal Investigator:
Ning Gao
Abstract:
This Small Business Innovation Research (SBIR) Phase I project will determine the feasibility of a polycapillary optics-based micro-x-ray absorption spectrometer (XAS) system with a low-power microfocus x-ray source by building a laboratory prototype. The system overcomes limitations of current… More

SBIR Phase II: New Convergent X-Ray Beam Based System for Protein Crystallography

Award Year / Program / Phase:
2004 / SBIR / Phase II
Award Amount:
$499,903.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase II project will develop a new convergent x-ray beam based crystallography system for measurement of the quality and the structure of protein crystals in an effort to support crystal growth development efforts and as a prescreening tool for very… More

Remote In-Situ Monitoring of Metal Contaminants in Groundwater with a Compact Grazing-Incident Monochromatic Microbeam X-Ray Fluorescence Analyzer

Award Year / Program / Phase:
2004 / SBIR / Phase I
Award Amount:
$99,940.00
Agency:
DOE
Principal Investigator:
Abstract:
75684-The evaluation of radionuclide and metal contaminants in the groundwater at DOE sites is typically done offsite using plasma mass spectroscopy or optical emission spectrometry. These analysis techniques are not suitable for automated field use because they require control gas or vacuum to… More

A Compact WDXRF Analyzer for Real-Time Monitoring of Heavy Metal Contaminants

Award Year / Program / Phase:
2005 / SBIR / Phase I
Award Amount:
$99,964.00
Agency:
DOE
Principal Investigator:
Abstract:
78242S Long-term and continuous monitoring of heavy metal contaminants in DOE tanks or DOE landfills has long been of great interest to DOE. Existing technologies either have the required detection sensitivity but are not field deployable, or are field deployable but lack the detection… More

Remote In-Situ Monitoring of Metal Contaminants in Groundwater with a Compact Grazing-Incident Monochromatic Microbeam X-Ray Fluorescence Analyzer

Award Year / Program / Phase:
2005 / SBIR / Phase II
Award Amount:
$749,315.00
Agency:
DOE
Principal Investigator:
Abstract:
75684S The evaluation of radionuclide and metal contaminants, found in the groundwater during the monitoring of DOE sites, is typically done off-site, using plasma mass spectroscopy or optical emission spectrometry. These analysis techniques are not suitable for automated field use because they… More

Remote Real Time Monitor for Elemental Speciation of Air Particulates

Award Year / Program / Phase:
2005 / SBIR / Phase I
Award Amount:
$69,922.00
Agency:
EPA
Principal Investigator:
Ning Gao, Senior Research Scientist
Abstract:
Air particulate has been identified as a souce of primary and secondary health risks. Even small, short-term increases in the amount of air particulte contamination in the atmosphere can produce significant increases in both mortality and morbidity from respiratory and cardiovasulare diseases. For… More

Direct Measurement of Trace Elements in Body Fluids

Award Year / Program / Phase:
2005 / SBIR / Phase I
Award Amount:
$95,187.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): Measurements of the composition of body fluids (urine, blood, plasma) are among the most important tools for disease detection and control. One class of measurement, less routinely applied but of increasing importance, is determination of trace element… More

Quantitave Analysis and Mapping of Metals in Tissues

Award Year / Program / Phase:
2005 / SBIR / Phase I
Award Amount:
$99,875.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): Bioessential metals operate at a delicate interface in biological systems between their essential functions and the destructive havoc they cause when they escape their normal control mechanisms. This is especially true for the so-called redox metals (Iron,… More

Development of portable single crystal residual stress analyzer

Award Year / Program / Phase:
2005 / SBIR / Phase I
Award Amount:
$99,595.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Huapeng Huang, research Scientist
Abstract:
Directionally solidified nickel superalloys are commonly used in turbine blades for high temperature aircraft and space propulsion engines and land-based, high-efficiency power generating plants. The surfaces of these parts are mechanically treated to provide compressive residual stress for… More

Development of a Portable XRD Grain Orientation Analyzer

Award Year / Program / Phase:
2005 / SBIR / Phase I
Award Amount:
$99,595.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Huapeng Huang, Research Scientist
Abstract:
Directionally solidified nickel superalloys are commonly used in turbine blades for high temperature aircraft and space propulsion engines and land-based, high-efficiency power generating plants. The casting of these parts does not always assure perfect crystal grain orientation which is critical… More

Remote Real Time Monitor for Elemental Speciation of Air Particulates

Award Year / Program / Phase:
2006 / SBIR / Phase II
Award Amount:
$341,682.00
Agency:
EPA
Principal Investigator:
Ning Gao, Senior Research Scientist
Abstract:
Air particulate has been identified as a source of primary and secondary health risks. More than 5000 air particulate monitoring stations have been established in the United States, mostly for measuring the total mass and the size distribution. Real-time monitoring instruments for mass and size… More

Lift Fan Gearbox Corrosion Monitoring System

Award Year / Program / Phase:
2006 / SBIR / Phase I
Award Amount:
$79,848.00
Agency / Branch:
DOD / NAVY
Principal Investigator:
Zewu Chen, Senior Rersearch Scientis
Abstract:
State-of-the-art gas turbine engine bearing and gearbox steels are subject to significant rejection rates due to corrosion. Recent statistics from the engine overhaul depots indicate that greater than 50 percent of the bearings are rejected. Approximately 40 percent of these rejections are due to… More

Development of a Portable XRD Grain Orientation Analyzer

Award Year / Program / Phase:
2007 / SBIR / Phase II
Award Amount:
$749,875.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Huapeng Huang, Research Scientist
Abstract:
Directionally solidified nickel superalloys are commonly used in turbine blades for high temperature aircraft and space propulsion engines and land-based, high-efficiency power generating plants. The casting of these parts does not always assure perfect crystal grain orientation that is critical… More

Quantitative Analysis and Mapping of Metals in Tissues

Award Year / Program / Phase:
2007 / SBIR / Phase II
Award Amount:
$1,140,034.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The objectives of this Phase II project are to develop and demonstrate a monochromatic-micro-x-ray fluorescence (MfXRF) instrument for high sensitivity and high spatial resolution (10-20 fm) mapping of trace metal distr ibutions in human brain tissue from… More

Direct Measurement of Trace Elements in Body Fluids

Award Year / Program / Phase:
2007 / SBIR / Phase II
Award Amount:
$1,141,134.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): This project involves development and application of a low-power, compact, reliable, easy to operate instrument for measurement of trace elements in body fluids (urine, blood, serum/plasma). The trace element analyzer c an be used in research clinic settings… More

SBIR Phase I: Development of XRD Based On-Line Characterization of Semicrystalline Plastics

Award Year / Program / Phase:
2008 / SBIR / Phase I
Award Amount:
$99,882.00
Agency:
NSF
Principal Investigator:
Abstract:
The Small Business Innovation Research (SBIR) Phase I project will investigate the feasibility for nondestructive, on-line monitoring of critical plastic film crystalline characteristics, including percent crystallinity, crystal size, and crystal orientation. Novel collimated polycapillary x-ray… More

Analyzer for Monitoring Personal Environmental Exposure to Fluids and Materials

Award Year / Program / Phase:
2008 / SBIR / Phase I
Award Amount:
$99,937.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The mission of the National Institutes of Health (NIH) is science in pursuit of fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to extend healthy life and red uce the burdens of illness and disability. … More

Development of On-Line XRD Pharmaceutical Process Analyzer

Award Year / Program / Phase:
2008 / SBIR / Phase I
Award Amount:
$99,313.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): This project involves development of a low-power, compact and portable, reliable, safe, and easy-to- operate x-ray diffraction instrument for measurement of crystal concentration and phase composition for active pharmac eutical ingredients (API) in the stages of… More

SBIR Phase I: Quantitative Analysis for Trace Levels of Toxic Elements in Consumer Products Using High Definition X-ray Fluorescence

Award Year / Program / Phase:
2009 / SBIR / Phase I
Award Amount:
$141,477.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research Phase I project proposes to demonstrate the feasibility of rapidly and quantitatively detecting ten different toxic elements found in consumer products with a portable high definition x-ray fluorescence (HDXRF) analyzer. The objective is to develop a new… More

Analyzer for monitoring personal environmental exposure to fluids and materials

Award Year / Program / Phase:
2009 / SBIR / Phase II
Award Amount:
$966,885.00
Agency:
HHS
Principal Investigator:
Matthew Cusack
Abstract:
DESCRIPTION (provided by applicant): The mission of the National Institutes of Health (NIH) is science in pursuit of fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to extend healthy life and red uce the burdens of illness and disability. … More

Online Optic Enabled X-Ray Analyzer for Fuel Cell Manufacturing

Award Year / Program / Phase:
2010 / SBIR / Phase I
Award Amount:
$149,994.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase I project seeks to demonstrate the feasibility of developing an online X-ray analyzer for real-time measurement of catalyst coating thickness of gas diffusion electrode (GDE). The electrodes in the fuel cell, either the single-element GDE, or an… More

SBIR Phase II:Quantitative Analysis for Trace Levels of Toxic Elements in Consumer Products Using High Definition X-ray Fluorescence

Award Year / Program / Phase:
2010 / SBIR / Phase II
Award Amount:
$499,998.00
Agency:
NSF
Principal Investigator:
Abstract:
This Small Business Innovation Research (SBIR) Phase II project will demonstrate rapid, nondestructive, quantitative analysis of trace-level toxic elements in both substrates and coated layers for consumer products in a device fit for purpose on a factory floor. Restrictions such as the Consumer… More

Rapid, Quantitative, Trace Element Measurement of Toxins in Consumer Products

Award Year / Program / Phase:
2011 / SBIR / Phase I
Award Amount:
$99,958.00
Agency:
HHS
Principal Investigator:
Danhong Li – 518-880-1500
Abstract:
DESCRIPTION (provided by applicant): The objective of this project is to demonstrate the feasibility of a nondestructive, compact, reliable, easy-to-operate X-ray fluorescence (XRF) analyzer for measurement of toxic elements in electronics and other related consumer products at their point of… More

Development of an online XRD pharmaceutical process analyzer

Award Year / Program / Phase:
2011 / SBIR / Phase II
Award Amount:
$1,120,833.00
Agency:
HHS
Principal Investigator:
David Gibson – 518-880-1500
Abstract:
DESCRIPTION (provided by applicant): Current pharmaceutical manufacturing technologies and processes are highly regulated and based on decades of experience. The techniques start in a lab, are continued in a pilot campaign, and finally graduate to full-scale manufacturing. To improve drug quality… More

Ultra-High Energy X-Ray Optics for Improved Assay of Nuclear Materials

Award Year / Program / Phase:
2011 / SBIR / Phase I
Award Amount:
$149,912.00
Agency:
DOE
Principal Investigator:
Danhong Li, Dr. – 518 880-1500
Abstract:
Current nuclear material measurement techniques are limited in the ability to assess the ratio of actinides such as curium (Cm) and plutonium (Pu) present in the sample from the beginning to the end of processing. As a result, it is difficult to discern whether nuclear material is safeguarded… More