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Kumakhow Optics for Clinical Dual-Energy Angiography

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
22309
Program Year/Program:
1993 / SBIR
Agency Tracking Number:
22309
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
X-RAY OPTICAL SYSTEMS, INC.
15 Tech Valley Drive East Greenbush, NY 12061-4134
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1993
Title: Kumakhow Optics for Clinical Dual-Energy Angiography
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

Conventional coronary angiography requires cardiac catheterization to inject an iodine contrast agent. If dual-energy digital subtraction angiography could be performed in clinical practice using intravenous iodine injections, patient risk could be substantially reduced. Additionally, x-ray exposure of the angiographer and other technical personnel during the catheter manipulation/placement would be eliminated. This project would evaluate combining two newly developed capabilities to achieve such a dual-energy angiography system. Science Research Laboratory (SRL) has constructed a compact high-flux characteristic-line x-ray anode source for dual-energy angiography. The effectiveness of this source would be greatly enhanced if the high energy continuum photon flux in the x-ray spectrum could be attenuated. Recent advances in Kumakhov optics utilizing x-ray capillary optics have demonstrated the ability to focus x-ray beams and to filter out high-energy photons. The expected result is a complete system would sequentially provide two very narrow x-ray spectra which bound the iodine K-edge for use in dual-energy digital subfraction angiography. The research performed in Phase I will establish the feasibility of filtering the characteristicline x-ray spectrum with a capillary optic. In Phase II, a Kumakhow x-ray will be constructed and tested with the SRL x-ray source.

Principal Investigator:

Qi-Fan Xiao
5184425250

Business Contact:

Small Business Information at Submission:

X-ray Optical Systems, Inc.
1400 Washington Avenue, Physic Albany, NY 12222

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No