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Displacement Chromatography of Coagulation Proteins

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
22354
Program Year/Program:
1993 / SBIR
Agency Tracking Number:
22354
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ZYMEQUEST, INC.
ZYMEQUEST, INC. 100 CUMMINGS CENTER BEVERLY, MA 01915-6122
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1993
Title: Displacement Chromatography of Coagulation Proteins
Agency: HHS
Contract: N/A
Award Amount: $49,680.00
 

Abstract:

It is proposed that coagulation factor proteins (VII, VIII, and IX) be purified by high resolution displacement chromatography directly from human plasma. Preliminary data shows that broad affinity displacers are effective in substantially purifying these proteins from each other and other plasma proteins. The displacer affinities that are effective in spacing these proteins will be determined and used to synthesize custom narrow-range displacers for large scale purifications. All purifications will be assayed with factor deficient substrate plasma, gel electrophoresis and immunoblots.

Principal Investigator:

Anthony R. Torres
8016267990

Business Contact:

Small Business Information at Submission:

Zymequest, Inc.
Science Laboratory Building, R Ogden, UT 84408

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No