DESCRIPTION (provided by investigator): Fluorogenic minor groove binder (MGB) probes containing an MGB-quencher at the 5'-end and a fluorophore at the 3'-end have been recently reported. These probes fluoresce on hybridization to the complementary targets. The 5'-MGB-quencher group prevents 5' -… More
DESCRIPTION (provided by applicant): Fluorogenic minor groove binder probes containing the MGB(tm) ligand at the 5'-end, an Eclipse(r) Dark Quencher and a fluorophore have been shown not to be degraded by 5'-nuclease activity. These probes, with excellent specificity and low fluorescent background… More
DESCRIPTION (provided by applicant): Bacterial and viral meningitis and encephalitis is a major cause of morbidity and mortality in all societies of the world. The rapid progression of symptoms and potentially devastating effect of these diseases necessita
te early recognition and immediate… More