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DECONTAMINATION OF PLATELET CONCENTRATES

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7322
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
7322
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Advanced Genetics Research
2220 Livington St Oakland, CA 94606
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1987
Title: DECONTAMINATION OF PLATELET CONCENTRATES
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE OVERALL OBJECTIVE OF THE RESEARCH IS TO DEFINE A SYSTEM FOR DECONTAMINATING PLATELET CONCENTRATES. PRESENT SCREENING OF DONATED BLOOD DOES NOT DETECT ALL POTENTIALLY INFECTIOUS CONTAMINANTS. THEREFORE, IT IS IMPORTANT TO FINDA MEANS OF RENDERING BLOOD PRODUCTS NONSPECIFICALLY NONINFECTIOUS TO REDUCE THE RISK OF VIRAL INFECTION AND BACTERIAL SEPSIS ASSOCIATED WITH THERAPEUTIC USE OF PLATELETCONCENTRATES. DIAMOND SCIENTIFIC COMPANY PROPOSES TO DEMONSTRATE THE ABILITY TO INACTIVATE AN ANIMAL-VIRUS MODEL IN PLATELET CONCENTRATES. THE EFFECTS OF THE INACTIVATION TREATMENT ON THE FOLLOWING WILL BE EXAMINED: (1) GROSS PLATELET MORPHOLOGY, BY MEASURING PLATELET COUNT AS A FUNCTION OF INACTIVATION TIME; (2) RESPONSE OF PLATELETS TO AGGREGATING AGENTS; AND (3) PLATELET ACTIVATION BY FLUORESCENT ANTIBODY ASSAY. THIS RESEARCH HAS THE POTENTIAL TO BE COMMERCIALLY USEFUL IN SAFEGUARDING THE ESTIMATED 5 TO 7 MILLION UNITS OF PLATELETS TRANSFUSED ANNUALLY.

Principal Investigator:

Gary p wiesehahn phd
5152629341

Business Contact:

Small Business Information at Submission:

Advanced Genetics Research
2220 Livington St Oakland, CA 94606

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No