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Company Information:

Company Name: ERCOLE BIOTECH, INC.
City: RESEARCH TRIANGLE PARK
State: NC
Zip+4: 27709
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
STTR Phase I $469,825.00 2
STTR Phase II $1,934,537.00 2

Award List:

Antisense Treatment for Thalassemia. Preclinical study.

Award Year / Program / Phase: 2004 / STTR / Phase I
Agency: HHS
Research Institution: UNIVERSITY OF NORTH CAROLINA CHAPEL HILL
Principal Investigator: Ryszard Kole
Award Amount: $270,674.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of… More

Antisense Treatment for Thalassemia. Preclinical study.

Award Year / Program / Phase: 2005 / STTR / Phase II
Agency: HHS
Research Institution: N/A
Principal Investigator: Ryszard Kole
Award Amount: $588,563.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of… More

Upregulation of soluble TNFR2 as treatment for Rheumatoid Arthritis

Award Year / Program / Phase: 2007 / STTR / Phase I
Agency: HHS
Research Institution: UNIVERSITY OF NORTH CAROLINA A
Principal Investigator: Peter Sazani
Award Amount: $199,151.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): The ultimate result of the proposed approach will be treatment for rheumatoid arthritis and possibly other diseases caused by the hyperactivity of TNF-a. The approach is to manipulate the alternative splicing pathways o f the TNF-a receptors (TNFR) pre- mRNA… More

Upregulation of soluble TNFR2 as treatment for Rheumatiod Arthritis

Award Year / Program / Phase: 2008 / STTR / Phase II
Agency: HHS
Research Institution: N/A
Principal Investigator: Peter Sazani
Award Amount: $1,345,974.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): The ultimate goal of this project, development of an anti-TNF-1 drug for rheumatoid arthritis and/or other TNF-1 induced inflammatory diseases, remains unchanged from the original application. The Phase II project will build on the Phase I identification of a… More