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Non Invasive Assessment of Intracranial Pressure and Cerebrovascular Status…

Award Information

Department of Defense
Office of the Secretary of Defense
Award ID:
Program Year/Program:
2009 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Infoscitex Corporation
303 Bear Hill Road Waltham, MA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2009
Title: Non Invasive Assessment of Intracranial Pressure and Cerebrovascular Status after Traumatic Brain Injury
Agency / Branch: DOD / OSD
Contract: W81XWH-09-C-0118
Award Amount: $99,852.00


Intracranial pressure, ICP, is arguably the single most important parameter used clinically to manage brain injury and long-term brain damage. Existing methods to record ICP are either invasive or require large equipment incompatible with a field deployable system. Our work combines two highly promising methods for monitoring ICP into a compact unit capable of continuous monitor. Using this bimodal approach will result in a single device that will lead to the definitive non-invasive device for monitoring ICP in far-field use. Our device incorporates retinal venous doppler ultrasonography (RVD) and pressure pulsatility analysis (PPA) into a single, compact unit safe for continuous automated use. We present innovations in PPA that enable continuous monitoring with more accurate readings from the RVD. Our device will enable monitoring of ICP on all patients with suspected brain injury, which will benefit the military as well as civilian health providers, from EMTs and paramedics to nurses and doctors in central hospitals.

Principal Investigator:

Anna Galea
Principal Engineer

Business Contact:

Stephen Mattox
Director, Finance & Contracts
Small Business Information at Submission:

303 Bear Hill Road Waltham, MA 02451

EIN/Tax ID: 043537120
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No