Fiscal Year:
2001
Title:
MICROWAVE RADIOMETERS FOR HYPERTHERMIA ANTENNA ARRAYS
Agency:
HHS
Contract:
N/A
Award Amount:
$101,989.00
Abstract:
DESCRIPTION (Adapted from Applicant's Abstract): The long-term objective of
this program is to improve the efficacy of hyperthermia treatments for patients
with superficial skin diseases that cover large areas overlying contoured
anatomies, such as chestwall recurrence of breast carcinoma or plaque
psoriasis, To accomplish this objective, we propose to incorporate microwave
radiometers that non-invasively measure subsurface tissue temperature into the
Conformed Hypethermia Array Applicator System already in clinical use at the
University of California, San Francisco (UCSF) to treat chestwall recurrence of
breast carcinoma. The incorporation of temperature sensors into the UCSF system
would make it possible to safely heat diseased tissues more uniformly and to
higher therapeutic temperatures than is possible now. This would significantly
increase the efficacy of the treatments and expand the number of patients with
superficial disease that can be treated effectively with hyperthermia. The
specific aim of the Phase I program is to develop a fast reading two frequency
microwave radiometer and integrate it into the multiple elements of the
Conformal Arrays. The goal of subsequent Phase II and III efforts will be to
set up the capability for production of low cost custom shaped (patient and
site specific) radiometrically controlled Conformal Arrays for heating large
area surface disease.
PROPOSED COMMERCIAL APPLICATION:
The proposed integration of non-invasive temperature sensing, using microwave radiometers,
with the hyperthermia antenna array should find wide use in clinics for treating superficial
tissue diseases such as chestwall recurrence of breast carcinoma and mild to moderate
plaque psoriasis. Celsion Corporation, a Silver Spring, MD manufacturer of hyperthermia
equipment which has licensed several MMTP patents, has expressed interest in
commercializing the radiometrically controlled Conformal Array applicator and multi-channel
915 MHz power equipment.
Principal Investigator:
Fred Sterzer
Small Business Information at Submission:
MMTC, INC.
12 ROSZEL RD, STE A-203 PRINCETON, NJ 08540
EIN/Tax ID:
222880210
DUNS:
N/A
Number of Employees:
N/A
Woman-Owned:
No
Minority-Owned:
No
HUBZone-Owned:
No