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Improved Protease Inhibitor Therapy for AIDS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29271
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29271
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Sts Duotek, Inc.
336 Summit Point Drive Henrietta, NY 14467
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Improved Protease Inhibitor Therapy for AIDS
Agency: HHS
Contract: 1 R43 CA68999-01,
Award Amount: $100,000.00
 

Abstract:

Our company will formulate a protease inhibitor, KNI-272, to improve bioavailability following oraladministration. This will be accomplished using patented technology to convert this nearly water-insspherical, amorphous, uniformly-sized submicron particles suspended in a biocompatible aqueous mediuhas been used to produce formulations for anti-cancer and antimicrobial therapy with improved oral bformulation of KNI-272 will be subjected to preliminary bioavailability evaluations in mice to demonPhase II objectives will focus on preclinical efficacy and toxicity studies following oral administrbenefits of intravenous administration. In Phase III, clinical trials will be carried out.

Principal Investigator:

Michael Violante
71633

Business Contact:

Small Business Information at Submission:

Sts Duotek, Inc.
336 Summit Point Drive Henrietta, NY 14467

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No