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Company Information:
Name:
VENATORX PHARMACEUTICALS, INC.
Address:
700 Pennsylvania Drive
EXTON, PA 19341-
EXTON, PA 19341-
Located in HUBZone:
No
Woman-Owned:
No
Minority-Owned:
No
URL:
N/A
Phone:
N/A
Award Totals:
Award List:
Novel Metallo-beta-lactamase Inhibitors
Award Year / Program / Phase:
2011 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Luigi Xerri – 484-595-6990
Award Amount:
$600,000.00
Abstract:
DESCRIPTION (provided by applicant): -lactam resistance conferred by zinc-based metallo- -lactamases (Amber Class B) is an emerging global health problem1-3. Members of this family of enzymes such as NDM-1 are found on mobile genetic elements which are rapidly spreading in Enterobacteriaceae and… More
Preserving beta-lactam utility against pathogens producing all classes of beta-la
Award Year / Program / Phase:
2011 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Christopher J. Burns – 610-213-0248
Award Amount:
$600,000.00
Abstract:
DESCRIPTION (provided by applicant): This Phase I SBIR Grant focuses on advancement of a new class of inhibitors of serine-based b-lactamases (Ambler classes A, C and D), for combination with the only subclass of b-lactams (the monobactams) that are not sensitive to zinc-based enzymes (Ambler Class… More
Novel Compounds Targeting Bacterial PBPs
Award Year / Program / Phase:
2012 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Christopher J. Burns – 610-213-0248
Award Amount:
$600,000.00
Abstract:
DESCRIPTION (provided by applicant): This Phase I SBIR Application centers on a new class of non-??-lactam antibacterial agents that target the same biological target as the ?-lactam class of antibiotics (i.e., the Penicillin Binding Proteins, or PBPs), but with the prospect of avoiding n important… More