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Laser Catheter for Bronchial Treatment of Severe Asthma

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
R43HL110585
Solicitation Year:
2011
Solicitation Topic Code:
NHLBI
Solicitation Number:
PA10-050
Small Business Information
BIOTEX, INC.
8058 EL RIO ST HOUSTON, TX -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: Laser Catheter for Bronchial Treatment of Severe Asthma
Agency: HHS
Contract: 1R43HL110585-01
Award Amount: $150,000.00
 

Abstract:

DESCRIPTION (provided by applicant): Asthma afflicts as many as 39 million Americans and some 4,000 will die of the disease each this year. The goal of this Phase I SBIR proposal is to design, develop, build, and test a novel, cooled laser catheter for effecting Bronchial Thermoplasty in a safe and efficient manner. Bronchial Thermoplasty is a relatively new term which refers to destruction of the muscular mucosa surrounding the bronchioles (tubular airway branches in the lungs) in an effort to defeat asthmatic airway constriction for the most severely afflicted patients. Recently, a radio-frequency (RF)-based device was introduced onto the market, but the device has drawbacks including the destruction of the endothelium which can result in worsening of condition in the short term. We believe that significant improvement may be obtained by employing a novel laser-based catheter system developed by BioTex for intraluminal sub-surface ablation which may result in faster therapeutic administration and should avoid destruction of the endothelial lining and the resulting sloughing process currently associated with RF- based methods. PUBLIC HEALTH RELEVANCE: The goal of this Phase I SBIR project is to develop a laser balloon catheter for reduction of symptoms in severe asthma by destroying the smooth muscle tissue which leads to asthma attacks . We will develop prototype catheters and test them in large animal subjects to verify performance in preparation for clinical studies in Phase II.

Principal Investigator:

Roger J. Mcnichols
713-741-0111
roger@biotexmedical.com

Business Contact:

Ashok Gowda
713-741-0111
ashok@biotexmedical.com
Small Business Information at Submission:

BIOTEX, INC.
8058 EL RIO ST HOUSTON, TX -

EIN/Tax ID: 174282404
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No