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Company Information:

Company Name:
LIFESPLICE PHARMA, LLC
Address:
1 Great Valley Parkway
Malvern, PA 19355-1423
Phone:
N/A
URL:
N/A
EIN:
127367480
DUNS:
965376994
Number of Employees:
N/A
Woman-Owned?:
Yes
Minority-Owned?:
No
HUBZone-Owned?:
No

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $953,009.00 2
SBIR Phase II $2,758,329.00 1

Award List:

Characterizing an AMPA Receptor Splice Modulator in Preventing Epileptogenesis

Award Year / Program / Phase:
2011 / SBIR / Phase I
Award Amount:
$494,735.00
Agency:
HHS
Principal Investigator:
Melanie K. Tallent – 610-347-2289
Abstract:
DESCRIPTION (provided by applicant): AMPA glutamate receptors mediate the majority of fast excitatory neurotransmission in the brain. Four AMPA receptor subunits exist, GluR1-GluR4, with functional channels containing various combinations of these foursubunits. In hippocampal and cortical… More

Oligonucleotides that Modulate AMPA Receptor Alternative Splicing as Drug Candida

Award Year / Program / Phase:
2011 / SBIR / Phase I
Award Amount:
$458,274.00
Agency:
HHS
Principal Investigator:
Gordon J. Lutz – 215-762-2396
Abstract:
DESCRIPTION (provided by applicant): Amyotrophic lateral sclerosis (ALS) is characterized by the progressive and selective loss of motor neurons (MNs) in the motor cortex, brainstem, and spinal cord, resulting in death of patients typically 2-5 years after diagnosis. Glutamate-mediated… More

Preclinical testing of the splice modulating oligonucleotide LSP-GR1

Award Year / Program / Phase:
2014 / SBIR / Phase II
Award Amount:
$2,758,329.00
Agency:
HHS
Principal Investigator:
Gordon J. Lutz – 610-296-5401
Abstract:
DESCRIPTION (provided by applicant): AMPA glutamate receptors mediate the majority of fast excitatory neurotransmission in the central nervous system. Four AMPA receptor subunits exist, GluA1-GluA4, with functional channels containing various combinationsof these four subunits. Dysregulation of AMPA… More