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Company Information:

Company Name: LIFESPLICE PHARMA, LLC
City: KENNETT SQUARE
State: PA
Zip+4: 19348-1017
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $953,009.00 2

Award List:

Characterizing an AMPA Receptor Splice Modulator in Preventing Epileptogenesis

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Melanie K. Tallent – 610-347-2289
Award Amount: $494,735.00
Abstract:
DESCRIPTION (provided by applicant): AMPA glutamate receptors mediate the majority of fast excitatory neurotransmission in the brain. Four AMPA receptor subunits exist, GluR1-GluR4, with functional channels containing various combinations of these foursubunits. In hippocampal and cortical… More

Oligonucleotides that Modulate AMPA Receptor Alternative Splicing as Drug Candida

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Gordon J. Lutz – 215-762-2396
Award Amount: $458,274.00
Abstract:
DESCRIPTION (provided by applicant): Amyotrophic lateral sclerosis (ALS) is characterized by the progressive and selective loss of motor neurons (MNs) in the motor cortex, brainstem, and spinal cord, resulting in death of patients typically 2-5 years after diagnosis. Glutamate-mediated… More