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High Throughput Manufacturing for Three-Dimensional Microfluidic Devices

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
R44EB012415
Solicitation Year:
2011
Solicitation Topic Code:
NIBIB
Solicitation Number:
PA09-113
Small Business Information
FEMTOFAB, INC.
24 Denby Rd Suite 120 Boston, MA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: High Throughput Manufacturing for Three-Dimensional Microfluidic Devices
Agency: HHS
Contract: 1R44EB012415-01
Award Amount: $67,200.00
 

Abstract:

DESCRIPTION (provided by applicant): Manufacturing based on photolithography has been responsible for ushering in the microelectronics era with enormous societal and economical impact. Extending microfabrication technology to 3D has the potential to revolutionize many diverse fields including biomedicine, energy conversation and storage, and photonic device manufacturing. While many 3D microfabrication techniques exist, they suffer from low throughput and/or low resolution. Importantly, these techniques arenot scalable; longer times are required to build larger devices. In this SBIR Fast Track proposal, FemtoFab Inc. seeks funding to demonstrate a novel microfabrication process, wide-field two-photon 3D lithography, which is based on temporal focusing of ultrafast light pulses. This new manufacturing technique, similar to standard 2D photolithography, is high throughput and scalable. Unlike standard photolithography, this technique is capable of manufacturing parts with 3D resolved feature. Among the many diverse applications of this 3D microfabrication process, FemtoFab Inc. has identified the manufacturing of microfluidic devices for biomedical applications as the most promising direction. In biomedicine, microfluidic devices have found applications in numerous areas, such as point-of- care diagnostic, drug discovery, and protein crystallization. The adaptation of wide-field two- photon 3D lithography for manufacturing will address the demand of microfluidic field for lower cost, higher density, and multi-functional devices. At the completion of Phase I, we will demonstrate the fabrication of microfluidic channels with complex 3D structures using this new technique. We will further quantify fabrication speed to prove that will additional investment in instrumentation will result in a microfabrication platform with industrial scale throughput. The additional resources during Phase II of this project will allow us to build and characterize an upgraded wide-field two-photon 3D lithographic microfabrication systemwith throughput and cost compatible with industrial scale manufacturing. We will further demonstrate the fabrication of complex 3D devices with integrated active microfluidic components such as pumps, valves at high speed and low cost. PUBLIC HEALTH RELEVANCE: In biomedicine, microfluidic devices have found applications in numerous areas, such as point- of-care diagnostic, drug discovery, and protein crystallization. We propose a novel high throughput 3D manufacturing process that addresses the demand of these applications for lower cost, higher density, and multi-functional devices.

Principal Investigator:

Yun-ho Jang
617-999-4977
yunhojang@gmail.com

Business Contact:

Daekeun Kim
617-398-0208
femtofab@gmail.com
Small Business Information at Submission:

FEMTOFAB, INC.
24 Denby Rd Suite 120 Boston, MA -

EIN/Tax ID: 127060567
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No