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Company Information:
Name:
TOLEROGENICS, INC.
Address:
20 NORTH WACKER
SUITE 1201
CHICAGO, IL 60606-
SUITE 1201
CHICAGO, IL 60606-
Located in HUBZone:
No
Woman-Owned:
No
Minority-Owned:
No
URL:
N/A
Phone:
N/A
Award Totals:
Award List:
Use of Bispecific Antibody for Treating Non-obese Diabetes
Award Year / Program / Phase:
2011 / STTR / Phase I
Agency:
HHS
Research Institution:
UNIVERSITY OF ILLINOIS AT CHICAGO
Abstract:
DESCRIPTION (provided by applicant): Activation of mature T lymphocytes is a multi-step process requiring both Ag-specific triggering of the TCR complex and co-stimulation mediated through the CD28-CD80/CD86 pathway. CTLA-4 is a critical inhibitor of T cell activation as evidenced by the lethal… More