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Magnetic Drive Mechanism for VF Doppler Smart Sensor

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2011 / STTR
Agency Tracking Number:
R41HL110430
Solicitation Year:
2011
Solicitation Topic Code:
NHLBI
Solicitation Number:
PA10-051
Small Business Information
ARBOR ULTRASOUND TECHNOLOGIES, LLC
6080 CRANE RD YPSILANTI, MI 48197-9029
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: Magnetic Drive Mechanism for VF Doppler Smart Sensor
Agency: HHS
Contract: 1R41HL110430-01
Award Amount: $101,323.00
 

Abstract:

DESCRIPTION (provided by applicant): Prior to dialysis vascular access failure (thrombosis), blood flow decreases from a baseline value to zero over some unknown time period. While the natural history and variation of flow prior to access failure is poorlyunderstood, it is known that customary monthly access flow monitoring is not frequent enough in many clinical settings for adequate prediction and prevention of an impending thrombosis. The effectiveness of access surveillance depends on the frequency andaccuracy with which monitoring can be performed. Therefore, the VF Doppler Automated Smart Sensor is being developed for continuous real-time flow monitoring during dialysis. We hypothesize that an active motion compensation/tracking control system utilizing feedback technology can be used to produce a commercially viable point-of-care Doppler based blood-flow monitoring device suitable for VF Doppler smart sensor (compact, low-cost, continuous) monitoring for dialysis and for general flow applications forvascular disease. Our research has determined that introducing active transducer motion compensation with the associated feedback mechanisms will allow for signal optimization improving blood flow measurement accuracy that has not been previously realized. Adding this active transducer drive capability introduces significant advantages for a commercializable device enabling practical clinical viability. Not only will it enhance the accuracy of the diagnostic flow measurement, but it also will allow measurements for broader vascular flow applications outside the dialysis setting. Therefore, this proposal will develop and evaluate a real-time transducer motion compensation system based on a magnetic drive mechanism for the VF (volume flow) Doppler smart sensor with feedback control. This proposal builds upon extensive work and will reduce the risk for successful commercial translation of this NIH sponsored technology. PUBLIC HEALTH RELEVANCE: This proposal will integrate a feedback control system and magnetic actuator into a compact, low-cost Doppler automated smart sensor for longitudinal operator-independent blood flow monitoring. This device will improve care and reduce cost for dialysis patients and patients with peripheral arterial disease.

Principal Investigator:

William F. Weitzel
734-615-3994
rick@arborultrasound.com

Business Contact:

Cheryl Weitxel
734-645-5896
cheryl@arborultrasound.com
Small Business Information at Submission:

ARBOR ULTRASOUND TECHNOLOGIES, LLC
6080 CRANE RD YPSILANTI, MI 48197-9029

EIN/Tax ID: 180066037
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
REGENTS OF THE UNIVERSITY OF MICHIGAN
3003 SOUTH STATE STREET
1040 Wolverine Tower
ANN ARBOR, MI 48109-1274
Contact: