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RAPID BREATH DETECTION OF LUNG CANCER

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
N43CO110066
Solicitation Year:
2011
Solicitation Topic Code:
NCI
Solicitation Number:
Small Business Information
ISENSE MEDICAL CORP.
500 AUSTRAILIAN AVE S STE 120 WEST PALM BEACH, FL 33401-6235
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: RAPID BREATH DETECTION OF LUNG CANCER
Agency: HHS
Contract: N43CO110066
Award Amount: $1,124,636.00
 

Abstract:

The sensitivity of iSense Medical Corp (IMC) sensor system for the detection of a lung cancer signature from breath will be enhanced and demonstrated, a new breath collection device completed and a modification of the Cleveland Clinic Foundation (CCF) protocol for the ELDDA study of 8000 lung cancer patients and controls will be completed. The first generation of this non-invasive, inexpensice and rapid assay for the presence of lunf cancer has already been tested at CCF wwith specificity and selectivity ofdetection in the 80s. The next generation of this sensor array,comprising optical indicators embedded in a nanoporous sol-gel matrix is now>100x more sensitive to a range of lung cancer breath markers, enhancing sensitivty for a breast sensor technology already proven effective in lung cancer detection. The approved CCF protocol will be refined to assess the specific claim that following an indeterminate lung CT witht he IMC breath test reduces lung cancer diagnosis false positives over 200%. Further, as lung cancer breath signature arises from active tumor metabolism, the protocol will be adapted to test the hypothesis that the IMC breath rest represents a rapid and low-cost assessment for the efficacy of chemotherapy.

Principal Investigator:

Paul Rhodes
650-298-9225
PRHODES@ISENSESYSTEMS.COM

Business Contact:

Paul Rhodes
650-298-9225
PRHODES@ISENSESYSTEMS.COM
Small Business Information at Submission:

ISENSE MEDICAL CORP.
500 AUSTRAILIAN AVE S STE 120 WEST PALM BEACH, FL 33401-6235

EIN/Tax ID: 999999999
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No