This statement of work concerns a contract for the proposed effort Production of Site?Specific O?GlcNAc Antibodies in response to Small Business Innovation Research (SBIR) Program PHS2011?1. The project seeks to produce monoclonal antibodies (MAbs) to three selected cancer?related protein… More
DESCRIPTION (provided by applicant): O-glycosylation of serine and threonine of nuclear and cytoplasmic proteins by a single beta-N- acetyl-D-glucosamine moiety (O-GlcNAc) is a ubiquitous post-translational modification that is highly dynamic and fluctuates in response to cellular stimuli. O-GlcNAc… More