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Company Information:

Name: ROCKLAND, INC.
Address: 650 ENGLESVILLE RD
BOYERTOWN, PA 19512-8407
Located in HUBZone: No
Woman-Owned: No
Minority-Owned: No
URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $149,866.00 1
SBIR Phase II $999,002.00 1

Award List:

TAS::75 0849::TAS SBIR TOPIC 292 PHASE I DEVELOPMENT OF MOLECULAR PHARMACODYNAMIC ASSAYS FOR TARGETED THERAPIES

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: David Chimento – 800-656-7625
Award Amount: $149,866.00
Abstract:
The RON and c-MET signal pathways are critical regulators of cell growth, survival, migration, differentiation, and drug resistance. High levels of activated RON or c-MET have been observed in a number of human cancers. Activation of RON and c-MET by phosphorylation initiates a signal transduction… More

SBIR TOPIC 229, PHASE II: PHARMACODYNAMIC ASSAY FOR AKT FOR USE WITH PI3K/AKT/MTOR INHIBITORS

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: David Chimento – 800-656-7625
Award Amount: $999,002.00
Abstract:
In response to this NCI solicitation, Rockland proposes to develop a novel method to assay the pharmacodynamic (PO) properties of anti-cancer small molecules targeting the PI3K/mTOR/AKT signaling pathway by quantitatively and independently measuring the phosphorylation of each unique AKT isoform in… More