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TAS::75 0849::TAS TOPIC 293, POINT OF CARE DEVICE FOR ANTIBODY INDEPENDENT…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
N43CO110114
Solicitation Year:
2011
Solicitation Topic Code:
NCI
Solicitation Number:
Small Business Information
APOCELL, INC.
2575 WEST BELLFORT, SUITE 190 HOUSTON, TX 77054-5029
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: TAS::75 0849::TAS TOPIC 293, POINT OF CARE DEVICE FOR ANTIBODY INDEPENDENT ISOLATION OF CIRCULATING TUMOR CELLS
Agency: HHS
Contract: N43CO110114
Award Amount: $198,812.00
 

Abstract:

Rare cell sublets in peripheral blood, such as circulating tumor cells (CTCs) has been used as biomarkers for cancer progression. In addition, growing evidence suggests that CTC isolation from a blood sample may allow reliable early detection and molecularcharacterization of cancer at diagnosis or relapse and provide a minimally-invasive method to guide and monitor the results of cancer therapy in cancer patients. Our goal is to commercialize a cost effective point of care device capable of isolating viable CTCs from a wide variety of cancers, for which proof of concept has been achieved in a research setting. For this Phase I proposal, we aim (1) to demonstrate the device feasibility for antibody independent isolation of viable CTCs, (2) to compare performance against the current FDA approved, state-of-the-art CTC isolation technology,and (3) characterize system performance. With the introduction of this technology, CTCs can be isolated from all metastatis cancers and provide a pre-screen diagnostic tool for cancer patients in a point of care setting. Also, unpurterbed and viable state of CTCs will allow systematic biological analysis of individual cells, permitting a personalized approach to cancer therapy.

Principal Investigator:

Darren Davis
713-440-6070
DDAVIS@APOCELL.COM

Business Contact:

Darren Davis
713-440-6070
DDAVIS@APOCELL.COM
Small Business Information at Submission:

APOCELL, INC.
2575 W BELLFORT ST STE 190 HOUSTON, TX 77054-5029

EIN/Tax ID: 161719463
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No