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Robust, animal-free cell culture medium for the production of vaccines

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
R43AI092916
Solicitation Year:
2011
Solicitation Topic Code:
NIAID
Solicitation Number:
PA10-050
Small Business Information
VENTRIA BIOSCIENCE
320 East Vine Drive FORT COLLINS, CO -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: Robust, animal-free cell culture medium for the production of vaccines
Agency: HHS
Contract: 1R43AI092916-01A1
Award Amount: $158,820.00
 

Abstract:

DESCRIPTION (provided by applicant): Epithelial cell lines such as Vero and MDCK are used in the production of viral based vaccines. The use of cell based vaccines is growing. The majority of the vaccines in use today are produced in medium supplemented with serum. The use of animal-derived products in vaccine culture media presents a risk for the transmission of infectious disease on a wide scale. Current commercially available serum-free vaccine media, are not defined, inconsistent, and do not offer the same performance as media supplemented with serum. We propose to produce a superior performance, defined, animal-free, cell culture medium for vaccine production. Our project addresses the call by agencies for a safe alternative to animal-derived componentsin vaccine production. PUBLIC HEALTH RELEVANCE: Epithelial cell lines such as Vero and MDCK are used in the generation of viral based vaccines and their use is expanding. Current commercially available animal-free vaccine production media are not defined and do not offer the same performance as media supplemented with serum. We propose the industry's first defined, high performance animal-free, cell culture medium to increase safety and the production of vaccines.

Principal Investigator:

Steve C. Pettit
919-824-9867
spettit@invitria.com

Business Contact:

Erik Vogel
970-219-3580
evogel@ventria.com
Small Business Information at Submission:

VENTRIA BIOSCIENCE
320 East Vine Drive FORT COLLINS, CO -

EIN/Tax ID: 168031084
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No