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Multiagent Synthetic DNA Vaccines Delivered by Noninvasive Electroporation

Award Information

Agency:
Department of Defense
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
A103-155-0133
Solicitation Year:
2010
Solicitation Topic Code:
A10-155
Solicitation Number:
2010.3
Small Business Information
Inovio Pharmaceuticals, Inc.
11494 Sorrento Valley Road Suite A San Diego, CA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: Multiagent Synthetic DNA Vaccines Delivered by Noninvasive Electroporation
Agency: DOD
Contract: W81XWH-11-C-0051
Award Amount: $69,670.00
 

Abstract:

Inovio Pharmaceuticals current minimally invasive dermal electroporation prototype device, which uses low voltage parameters to achieve both high and consistent levels of immunogenicity, offers an attractive option as an efficient and tolerable method for delivering DNA vaccinations in a clinical setting. For this submission, we propose to develop a multi-headed electroporation platform based on optimized version of the current device. This new device would remain an effective means to deliver DNA vaccines while maintaining the tolerability of a surface dermal electroporation method. Additionally, this device could simultaneously delivery two or more DNA vaccines at spatially separate sites, negating any issues with interference and reducing vaccine burden. The production of such a device which could simultaneously deliver multiple plasmid vaccines would offer a significant advance in the field of DNA vaccinations.

Principal Investigator:

Kate Broderick
Associate Director, R&D
(858) 410-3161
kbroderick@inovio.com

Business Contact:

Niranjan Sardesai
Sr VP, Research&Development
(267) 440-4232
nsardesai@inovio.com
Small Business Information at Submission:

Inovio Pharmaceuticals, Inc.
11494 Sorrento Valley Road Suite A San Diego, CA -

EIN/Tax ID: 330969592
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No