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Software Tool for Complex Biomarker Discovery

Award Information

Agency:
Department of Defense
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
A103-159-0107
Solicitation Year:
2010
Solicitation Topic Code:
A10-159
Solicitation Number:
2010.3
Small Business Information
TopGear Automation
567 Riverbend Pearisburg, VA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: Software Tool for Complex Biomarker Discovery
Agency: DOD
Contract: W81XWH-11-C-0041
Award Amount: $69,758.00
 

Abstract:

A new algorithm is proposed to identify hazards based on high-fidelity correlation between gene expressions and pathway signals. A software implementation based on'energy score'method has been developed to detect multiple gene interactions in the pursuit of specific signal pathways within key cells of interest. This method, Graphical Random Walk (GRW) is robust, highly sensitive, and unlike methods of binary descent, can detect very low continuous exposures. Proof of feasibility and the application of this methodology toward monitoring for toxic threats and exposures will provide the US Army with a significantly improved defense against short term and long term threats.

Principal Investigator:

Brett Malone
President
(540) 250-1628
bmalone@topgearautomation.com

Business Contact:

Brett Malone
President
(540) 250-1628
bmalone@topgearautomation.com
Small Business Information at Submission:

TopGear Automation
567 Riverbend Pearisburg, VA -

EIN/Tax ID: 208121281
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: Yes