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KINETICALLY CONTROLLABLE, THERAPEUTIC TOPICAL DELIVERY OF NITRIC OXIDE THROUGH…

Award Information

Agency:
Department of Defense
Branch:
N/A
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
A103-160-0457
Solicitation Year:
2010
Solicitation Topic Code:
A10-160
Solicitation Number:
2010.3
Small Business Information
iFyber, LLC
950 Danby Road, Suite 300 Ithaca, NY 14850-5714
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2011
Title: KINETICALLY CONTROLLABLE, THERAPEUTIC TOPICAL DELIVERY OF NITRIC OXIDE THROUGH NOVEL BIODEGRADABLE"PSEUDO-PROTEIN"BIOMATERIALS
Agency: DOD
Contract: W81XWH-11-C-0032
Award Amount: $69,900.00
 

Abstract:

iFyber LLC, the lead company for this project, will partner with Prof. CC Chu from Cornell University, a recognized expert in the development and study of new drug-eluting biomaterials for wound healing, to develop a platform technology for controlled release of nitric using a newly invented family of novel biodegradable amino acid-based poly(ester amide)s (AA-PEAs). These pseudo-protein biomaterials have been engineered into different physical forms including gels, fibrous membranes, micro/nanospheres. These novel pseudo-protein biomaterials have already been demonstrated in vitro and in vivo to elicit far lower levels of inflammation than existing FDA-approved commercial biomaterials. The current efforts will exploit AA-PEA-based biodegradable biomaterials that are enzymatically biodegradable and have pendant functional groups that can be used to conjugate condensed-phase nitric oxide (NO) moieties. Controlled release of nitric oxide with be fine-tuned using a combination of NO moiety breakdown and enzymatic biodegradation of the NO-containing AA-PEA biomaterials.

Principal Investigator:

Aaron D. Strickland
VP, Research and Development
(607) 227-7522
astrick@ifyber.com

Business Contact:

Eric Eisenhut
President
(607) 330-2307
ee@ifyber.com
Small Business Information at Submission:

IFyber, LLC
950 Danby Road Suite 300 Ithaca, NY -

EIN/Tax ID: 263310485
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No