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Neuromonitoring of Traumatic Brain/blast Injury

Award Information

Agency:
Department of Defense 		Branch:
Defense Health Program 		Award ID:
 Program Year/Program:
2011 / SBIR
Agency Tracking Number:
O2-1083 		Solicitation Year:
2009 		Solicitation Topic Code:
OSD09-H06 		Solicitation Number:
2009.3
Small Business Information
ADVANCED BRAIN MONITORING
2237 Faraday Ave Suite 100 Carlsbad, CA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2011
Title: Neuromonitoring of Traumatic Brain/blast Injury
Agency / Branch: DOD / DHP
Contract: W81XWH-10-C-0061
Award Amount: $749,994.00
 

Abstract:

It is well known that the brain is the organ most sensitive to ischemia/hypoxia. Noninvasive continuous monitoring of cerebral blood flow autoregulation, cerebrovascular reactivity and related phenomena such as cerebral vasospams in combat casualties could guide clinicians/medics in adjusting the strategy of resuscitation and acute care, and therefore contribute to a substantially improved survival and functional outcome. In Phase I we developed a small (3.5 x 2.5 x 0.7 in), light-weight (<4oz), battery powered and hand-portable 3-channel monitor that combines electro- and rheoencephalography (EEG and REG). While REG detects changes in cerebral vascular bed, EEG can be used to detect post-traumatic non-convulsive seizures or reversible breakdown of the synaptic transmission. The monitor can transfer the data in real time via either a Bluetooth link or standard USB connection. The monitor also has sufficient memory to store the raw data from>300 hours of recording. In Phase II we propose to ruggedize the Phase I monitor so to make it truly field-deployable, and to in part directly organize, and in part support, a number of animal and human studies (including a study on TBI patients) that should provide evidence of the efficacy of the monitor.

Principal Investigator:

Djordje Popovic
Director of Research
(760) 720-0099
dpopovic@b-alert.com

Business Contact:

Sandy Crow
VP of Government Contract
(760) 720-0099
scrow@b-alert.com
Small Business Information at Submission:

Advanced Brain Monitoring
2237 Faraday Ave Suite 100 Carlsbad, CA -

EIN/Tax ID: 330886301
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No